Esen Ebru, Sizmaz Selcuk, Demircan Nihal
Department of Ophthalmology, School of Medicine, Cukurova University, Adana, Turkey.
Retin Cases Brief Rep. 2016 Spring;10(2):154-6. doi: 10.1097/ICB.0000000000000213.
To present two cases of acute endophthalmitis after intravitreal dexamethasone implant injection and discuss the management of intravitreal implant-associated endophthalmitis.
Two patients, who underwent intravitreal dexamethasone implant injection for macular edema secondary to diabetic retinopathy in one and branch retinal vein occlusion in the other, were admitted with decreased vision, pain, and redness in their treated eyes, 3 days and 5 days after the injection, respectively. The clinical findings of both patients were consistent with acute endophthalmitis.
After obtaining aqueous and vitreous samples, the patients were treated with intravitreal antibiotic injection and topical fortified antibiotics. Both patients revealed favorable clinical response and functional vision was recovered.
Intravitreal dexamethasone implant-associated endophthalmitis is an uncommon and a challenging situation. Intravitreal antibiotics may lead to favorable visual outcomes without the need for a pars plana vitrectomy and implant removal in selected cases.
介绍两例玻璃体内注射地塞米松植入剂后发生急性眼内炎的病例，并讨论玻璃体内植入物相关眼内炎的处理方法。
两名患者分别因糖尿病性视网膜病变继发黄斑水肿（其中一例）和视网膜分支静脉阻塞（另一例）接受玻璃体内地塞米松植入剂注射，分别在注射后3天和5天因患眼视力下降、疼痛和眼红而入院。两名患者的临床表现均符合急性眼内炎。
采集房水和玻璃体样本后，对患者进行玻璃体内抗生素注射和局部强化抗生素治疗。两名患者均显示出良好的临床反应，视力功能得以恢复。
玻璃体内地塞米松植入物相关眼内炎是一种罕见且具有挑战性的情况。在某些病例中，玻璃体内注射抗生素可能无需进行玻璃体切割术和平部玻璃体切除术及取出植入物即可带来良好的视觉效果。
