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内科收治的脓毒症患者预后的临床预测准确性。

The accuracy of clinical prediction of prognosis for patients admitted with sepsis to internal medicine departments.

作者信息

Ghanem-Zoubi Nesrin, Bitterman Haim, Laor Arie, Yurin Vitaly, Vardi Moshe

机构信息

a Infectious Diseases Unit , Rambam Health Care Campus , Haifa , Israel.

b Internal Medicine Department , Carmel Medical Center , Haifa , Israel.

出版信息

Ann Med. 2015;47(7):555-60. doi: 10.3109/07853890.2015.1089361. Epub 2015 Oct 1.

Abstract

INTRODUCTION

Prognosis estimation offered by physicians for patients inflicted by sepsis on their admission to Internal Medicine (IM) departments is considered a challenge. Early prognosis estimation is critical and determines the intensity of treatment offered. The accuracy of prognosis estimation made by physicians has previously been investigated mainly among intensive care physicians and oncologists.

OBJECTIVE

To ascertain the accuracy of prognosis prediction made by internists for septic patients on admission to IM departments.

METHODS

Physicians were asked to estimate the prognosis of every patient identified to have sepsis on admission. Their intuitive assessment of prognosis was incorporated into the patients' electronic medical record. Survival follow-up was recorded until death or for at least 2 years. Later we compared survival with physicians' prognosis estimations.

RESULTS

Prognosis estimation was recorded for 1,073 consecutive septic patients admitted throughout the years 2008-2009 to IM departments. The mean age of patients was 74.7 ± 16.1 years. A total of 42.4% were suspected to have pneumonia, and 65.4% died during a mean follow-up time of 661.1 ± 612.3 days. Almost half of the patients classified to have good prognosis survived compared to 14.9% and 4.9% of those with intermediate and bad prognosis estimation, respectively (P < 0.001).

CONCLUSION

Internists can discriminate well between septic patients with good, intermediate, and bad prognosis.

摘要

引言

内科医生对脓毒症患者入院时的预后评估被认为是一项挑战。早期预后评估至关重要,并决定了所提供治疗的强度。此前,主要在重症监护医生和肿瘤学家中研究了医生进行的预后评估的准确性。

目的

确定内科医生对脓毒症患者入院时预后预测的准确性。

方法

要求医生评估每位入院时被确定患有脓毒症的患者的预后。他们对预后的直观评估被纳入患者的电子病历。记录生存随访情况直至死亡或至少持续2年。之后,我们将生存率与医生的预后评估进行比较。

结果

记录了2008年至2009年期间连续入住内科病房的1073例脓毒症患者的预后评估情况。患者的平均年龄为74.7±16.1岁。共有42.4%的患者疑似患有肺炎,在平均661.1±612.3天的随访期内,65.4%的患者死亡。被分类为预后良好的患者中,近一半存活,而预后评估为中等和差的患者中,存活比例分别为14.9%和4.9%(P<0.001)。

结论

内科医生能够很好地区分预后良好、中等和较差的脓毒症患者。

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