异基因骨髓移植后发生急性移植物抗宿主病的患者出现肠道阿米巴病，经甲硝唑成功治疗。

Intestinal amoebiasis in a patient with acute graft-versus-host disease after allogeneic bone marrow transplantation successfully treated by metronidazole.

作者信息

Numata A, Itabashi M, Kishimoto K, Motohashi K, Hagihara M, Kuwabara H, Tanaka M, Kato H, Chiba S, Kunisaki R, Fujisawa S

机构信息

Department of Hematology, Yokohama City University Medical Center, Yokohama, Japan.

Infection Control Department, Yokohama City University Medical Center, Yokohama, Japan.

出版信息

Transpl Infect Dis. 2015 Dec;17(6):886-9. doi: 10.1111/tid.12460. Epub 2015 Nov 25.

DOI:10.1111/tid.12460

PMID:26426525

Abstract

Amoebiasis has rarely been reported in patients undergoing hematopoietic stem cell transplantation, although it is a world-wide infection and extremely common. We present a case of intestinal amoebiasis unexpectedly revealed by colonoscopy after allogeneic bone marrow transplantation from a human leukocyte antigen-mismatched unrelated donor for acute myeloid leukemia arising from chronic myelomonocytic leukemia and successfully treated by metronidazole.

摘要

尽管阿米巴病是一种全球范围内的感染且极为常见，但在造血干细胞移植患者中鲜有报道。我们报告一例肠道阿米巴病病例，该病例是在一名慢性粒单核细胞白血病继发急性髓系白血病患者接受来自人类白细胞抗原不匹配的无关供者的异基因骨髓移植后，通过结肠镜意外发现的，并经甲硝唑成功治疗。