Li Teng-Fei, Shui Shao-Feng, Han Xin-Wei, Yan Lei, Ma Ji, Guo Dong, Zhu Hong-Can, Wang Shu-Kai, He Yuan-Hong, Chen Wen-Wu, Wei Li-Ping, Wang Ming-Ke, Song Tai-Min
Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Interventional Institute of Zhengzhou University, Zhengzhou, China.
Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
PLoS One. 2015 Oct 1;10(10):e0139714. doi: 10.1371/journal.pone.0139714. eCollection 2015.
The Solitaire AB stent is one of many assistant stents used for treating wide-necked cerebral aneurysm, and has been used since 2003. However, large sample studies on its safety and effectiveness are lacking. The objective of this study was to evaluate the effectiveness and safety of the Solitaire AB stent in the coil embolization of wide-necked cerebral aneurysms.
Retrospective review of the clinical and image data of 116 patients with wide-necked cerebral aneurysms who had been enrolled at six interventional neuroradiology centers from February 2010 to February 2014 and had been treated by coil embolization; in total, 120 Solitaire AB stents were used. The degree of aneurysm occlusion was examined using digital subtraction angiography (DSA) immediately after the procedure and during follow-up, and was graded using the modified Raymond classification. We also observed complications to evaluate the safety and effectiveness of this therapy.
The 120 Solitaire AB stents (4 mm × 15 mm, four stents; 4 mm × 20 mm, 16 stents; 6 mm × 20 mm, 36 stents; 6 mm × 30 mm, 64 stents) were inserted to treat 120 wide-necked cerebral aneurysms. All stents were inserted successfully. DSA immediately post-surgery revealed 55 cases of complete occlusion, 59 cases of neck remnant, and six cases of aneurysm remnant. Perioperatively, there were four cases of hemorrhage and four cases of stent thrombosis. The follow-up spanned 3-37 months; of 92 patients examined by DSA at the 6-month follow up, 12 had disease recurrence.
The Solitaire AB stent is effective with a good technical success rate and short-term effect for assisting coil embolization of wide-necked cerebral aneurysms.
Solitaire AB支架是用于治疗宽颈脑动脉瘤的众多辅助支架之一,自2003年起开始使用。然而,缺乏关于其安全性和有效性的大样本研究。本研究的目的是评估Solitaire AB支架在宽颈脑动脉瘤弹簧圈栓塞治疗中的有效性和安全性。
回顾性分析2010年2月至2014年2月期间在6个介入神经放射中心登记并接受弹簧圈栓塞治疗的116例宽颈脑动脉瘤患者的临床和影像资料;共使用了120个Solitaire AB支架。术后即刻及随访期间采用数字减影血管造影(DSA)检查动脉瘤闭塞程度,并采用改良Raymond分级法进行分级。我们还观察并发症以评估该治疗方法的安全性和有效性。
120个Solitaire AB支架(4mm×15mm,4个支架;4mm×20mm,16个支架;6mm×20mm,36个支架;6mm×30mm,64个支架)被植入以治疗120个宽颈脑动脉瘤。所有支架均成功植入。术后即刻DSA显示完全闭塞55例,颈部残留59例,动脉瘤残留6例。围手术期有4例出血和4例支架血栓形成。随访时间为3 - 37个月;在6个月随访时接受DSA检查的92例患者中,有12例疾病复发。
Solitaire AB支架在辅助宽颈脑动脉瘤弹簧圈栓塞治疗中技术成功率高、短期效果良好且有效。