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青少年胸腰椎结核手术的治疗效果、术后并发症及其原因

Treatment effect, postoperative complications, and their reasons in juvenile thoracic and lumbar spinal tuberculosis surgery.

作者信息

He Qing-Yi, Xu Jian-Zhong, Zhou Qiang, Luo Fei, Hou Tianyong, Zhang Zehua

机构信息

Department of Orthopedics, Southwest Hospital, Third Military Medical University, No. 30 Gaotanyan Street Shapingba District, Chongqing, 400038, China.

出版信息

J Orthop Surg Res. 2015 Oct 1;10:156. doi: 10.1186/s13018-015-0300-y.

Abstract

OBJECTIVE

Fifty-four juvenile cases under 18 years of age with thoracic and lumbar spinal tuberculosis underwent focus debridement, deformity correction, bone graft fusion, and internal fixation. The treatment effects, complications, and reasons were analyzed retrospectively.

MATERIAL AND METHOD

There were 54 juvenile cases under 18 years of age with thoracolumbar spinal tuberculosis. The average age was 9.2 years old, and the sample comprised 38 males and 16 females. The disease types included 28 thoracic cases, 17 thoracolumbar cases, and 9 lumbar cases. Nerve function was evaluated with the Frankel classification. Thirty-six cases were performed with focus debridement and deformity correction and were supported with allograft or autograft in mesh and fixed with pedicle screws from a posterior approach. Eight cases underwent a combined anterior and posterior surgical approach. Nine cases underwent osteotomy and deformity correction, and one case received focus debridement. The treatment effects, complications, and bone fusions were tracked for an average of 52 months.

RESULTS

According to the Frankel classification, paralysis was improved from 3 cases of B, 8 cases of C, 18 cases of D, and 25 cases of E preoperatively. This improvement was found in 3 cases of C, 6 cases of D, and 45 cases of E at a final follow-up postoperatively. No nerve dysfunction was aggravated. VAS was improved from 7.8 ± 1.7 preoperatively to 3.2 ± 2.1 at final follow-up postoperatively. ODI was improved from 77.5 ± 17.3 preoperatively to 28.4 ± 15.9 at final follow-up postoperatively. Kyphosis Cobb angle improved from 62.2° ± 3.7° preoperatively to 37° ± 2.4° at final follow-up postoperatively. Both of these are significant improvements, and all bone grafts were fused. Complications related to the operation occurred in 31.5% (17/54) of cases. Six cases suffered postoperative aggravated kyphosis deformity, eight cases suffered proximal kyphosis deformity, one case suffered pedicle penetration, one case suffered failure of internal devices, and one case suffered recurrence of tuberculosis.

CONCLUSION

As long as the treatment plan is fully prepared, the surgical option can achieve a satisfactory curative effect in treating juvenile spinal tuberculosis despite some complications.

摘要

目的

对54例18岁以下的青少年胸腰椎脊柱结核患者进行病灶清除、畸形矫正、植骨融合及内固定治疗。回顾性分析其治疗效果、并发症及原因。

材料与方法

54例18岁以下青少年胸腰椎脊柱结核患者,平均年龄9.2岁,其中男性38例,女性16例。疾病类型包括胸椎结核28例、胸腰椎结核17例、腰椎结核9例。采用Frankel分级评估神经功能。36例行病灶清除及畸形矫正,采用同种异体骨或自体骨网植骨,并经后路椎弓根螺钉固定。8例行前后联合手术入路。9例行截骨及畸形矫正,1例行病灶清除。平均随访52个月,观察治疗效果、并发症及植骨融合情况。

结果

根据Frankel分级,术前B级3例、C级8例、D级18例、E级25例存在瘫痪,术后末次随访时C级3例、D级6例、E级45例瘫痪情况得到改善,无神经功能障碍加重。视觉模拟评分(VAS)术前为7.8±1.7,术后末次随访时为3.2±2.1。功能障碍指数(ODI)术前为77.5±17.3,术后末次随访时为28.4±15.9。后凸Cobb角术前为62.2°±3.7°,术后末次随访时为37°±2.4°。均有显著改善,所有植骨均融合。手术相关并发症发生率为31.5%(17/54)。6例术后后凸畸形加重,8例近端后凸畸形,1例椎弓根穿透,1例内固定失败,1例结核复发。

结论

只要充分做好治疗方案准备,手术治疗青少年脊柱结核虽有一些并发症,但仍可取得满意疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab8/4590253/1e67a6506801/13018_2015_300_Fig1_HTML.jpg

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