Khan Mohammed Nazir, Guranda Mihail, Essig Marco
Department of Radiology, University of Manitoba, Winnipeg, Canada
Department of Internal Medicine, Section of Neurology, University of Manitoba, Winnipeg, Canada.
Neuroradiol J. 2015 Oct;28(5):493-7. doi: 10.1177/1971400915609798. Epub 2015 Oct 1.
Tumefactive demyelination refers to large focal demyelinating lesions in the brain, which can be mistaken for malignancy. In some patients, these lesions are monophasic with a self-limited course; however, other patients demonstrate recurrent disease with new tumefactive or non-tumefactive lesions, and a subsequent diagnosis of relapsing-remitting multiple sclerosis is not uncommon. Owing to the limited data available in the literature, many questions about the patterns and prognostic significance of recurrent tumefactive lesions remain unanswered. The current case report involves a patient who recovered from tumefactive demyelination and presented two years later with a new recurrent tumefactive lesion in the contralateral brain.
瘤样脱髓鞘病变是指大脑中较大的局灶性脱髓鞘病变，可被误诊为恶性肿瘤。在一些患者中，这些病变呈单相病程且具有自限性；然而，其他患者会出现复发性疾病，伴有新的瘤样或非瘤样病变，随后诊断为复发缓解型多发性硬化症的情况并不少见。由于文献中的数据有限，许多关于复发性瘤样病变的模式和预后意义的问题仍未得到解答。本病例报告涉及一名从瘤样脱髓鞘病变中康复的患者，两年后在对侧大脑出现了新的复发性瘤样病变。
