Quarto Gennaro, Genovese Giuseppe, Apperti Marco, Amato Bruno, Benassai Giacomo, Furino Ermenegildo
Ann Ital Chir. 2015;86:427-31.
Research of a starting point to debate about the possibility of identifying a unique sign of previous DVT.
A retrospective study involving 202 outpatients with venous insufficiency of the lower limbs (CEAP classes C 4/6), classified according to the affected venous district. Patients positive for deep vein thrombosis (DVT) were subjected to Compression Ultra Sound test (CUS test) with measurement of the wall thickness at the point of formation of the thrombus and at fixed points of common femoral and popliteal veins used also in the patients with negative history of DVT RESULTS: Among total group, only 19 patients (9.40%) had an history of DVT. No one of them had a superficial incontinence. The measurement of wall thickness in positive DVT history patients (group A) resulted in an average value of 1.10 mm (s.d=0.06), while the average value obtained in negative DVT history (group B) was 0.55 mm (s.d.= 0.20). However, in 13 patients wall thickness was > 1mm (mean: 1.04 mm). The difference between the averages of group A and B was statistically significant (p <0.05).
In all positive DVT history patients and in 13 ones with negative history we found an increase in wall thickness, with a value > 1 mm. Can the wall thickening more than 1 mm be considered an indicator of previous DVT? Can it be considered a "marker" for thrombophilia status?
The usefulness of a sign of previous DVT (even if asymptomatic), detected during a routine Doppler ultrasound check of lower limbs, could be a warning bell to investigate thrombophilia status.
Chronic Venous Insufficiency, Duplex ultrasound, Hypercoagulability, Post-thrombotic Syndrome, Venous Thromboembolism.
研究关于识别既往深静脉血栓形成独特体征可能性的争论起点。
一项回顾性研究，纳入202例下肢静脉功能不全门诊患者（CEAP分级C 4/6级），根据受累静脉区域进行分类。深静脉血栓形成（DVT）阳性患者接受压迫超声检查（CUS检查），测量血栓形成部位以及股总静脉和腘静脉固定点处的管壁厚度，DVT病史阴性患者也采用这些固定点进行测量。结果：在整个研究组中，仅有19例患者（9.40%）有DVT病史。他们中无人有浅静脉功能不全。有DVT病史阳性患者组（A组）的管壁厚度测量平均值为1.10毫米（标准差=0.06），而DVT病史阴性患者组（B组）获得的平均值为0.55毫米（标准差=0.20）。然而，有13例患者的管壁厚度>1毫米（平均值：1.04毫米）。A组和B组平均值之间的差异具有统计学意义（p<0.05）。
在所有有DVT病史阳性患者以及13例有DVT病史阴性患者中，我们发现管壁厚度增加，值>1毫米。管壁增厚超过1毫米能否被视为既往DVT的指标？它能否被视为血栓形成倾向状态的“标志物”？
在下肢常规多普勒超声检查期间检测到的既往DVT体征（即使无症状）的有用性，可能是调查血栓形成倾向状态的警钟。
慢性静脉功能不全、双功超声、高凝状态、血栓形成后综合征、静脉血栓栓塞症
