Nakai I, Aikawa I, Oka T
Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
Diabetes. 1989 Jan;38 Suppl 1:111-3. doi: 10.2337/diab.38.1.s111.
The changes of the microvasculature of rat pancreas transplants during acute rejection were investigated and quantitatively analyzed. The vessels in pancreas transplants increased in caliber and decreased in density during acute rejection. These changes were marked in the exocrine pancreas, especially in central zones, whereas changes in islets were mild. These results indicate that the early deterioration of exocrine function is closely related to vascular destruction.
研究并定量分析了大鼠胰腺移植急性排斥反应期间微血管系统的变化。胰腺移植中的血管在急性排斥反应期间管径增大而密度降低。这些变化在外分泌胰腺中明显,尤其是在中央区域,而胰岛的变化则较轻。这些结果表明外分泌功能的早期恶化与血管破坏密切相关。