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大鼠胰腺移植急性排斥反应中微血管系统的定量分析

Quantitative analysis of microvasculature of rat pancreas transplants in acute rejection.

作者信息

Nakai I, Aikawa I, Oka T

机构信息

Department of Surgery, Kyoto Prefectural University of Medicine, Japan.

出版信息

Diabetes. 1989 Jan;38 Suppl 1:111-3. doi: 10.2337/diab.38.1.s111.

DOI:10.2337/diab.38.1.s111
PMID:2642830
Abstract

The changes of the microvasculature of rat pancreas transplants during acute rejection were investigated and quantitatively analyzed. The vessels in pancreas transplants increased in caliber and decreased in density during acute rejection. These changes were marked in the exocrine pancreas, especially in central zones, whereas changes in islets were mild. These results indicate that the early deterioration of exocrine function is closely related to vascular destruction.

摘要

研究并定量分析了大鼠胰腺移植急性排斥反应期间微血管系统的变化。胰腺移植中的血管在急性排斥反应期间管径增大而密度降低。这些变化在外分泌胰腺中明显,尤其是在中央区域,而胰岛的变化则较轻。这些结果表明外分泌功能的早期恶化与血管破坏密切相关。

相似文献

1
Quantitative analysis of microvasculature of rat pancreas transplants in acute rejection.大鼠胰腺移植急性排斥反应中微血管系统的定量分析
Diabetes. 1989 Jan;38 Suppl 1:111-3. doi: 10.2337/diab.38.1.s111.
2
Quantitative analysis of the microvasculature of rat pancreas transplants during the acute rejection process.大鼠胰腺移植急性排斥反应过程中微血管系统的定量分析。
Transplant Proc. 1989 Feb;21(1 Pt 1):502-4.
3
Morphology of acute rejection and corresponding cytological findings in exocrine secretion after pancreas transplantation in the rat.大鼠胰腺移植后急性排斥反应的形态学及外分泌分泌物中的相应细胞学发现
Transplantation. 1991 Nov;52(5):770-7. doi: 10.1097/00007890-199111000-00003.
4
Identical pattern of acute rejection after isolated islet and vascularized whole-pancreas transplantation in the rat.大鼠胰岛移植和血管化全胰腺移植后急性排斥反应的相同模式。
Am J Pathol. 1990 Jul;137(1):93-102.
5
Contribution of nonendocrine tissue to the immunogenicity of endocrine pancreatic transplants.非内分泌组织对内分泌胰腺移植免疫原性的作用。
Transplant Proc. 1990 Oct;22(5):2331.
6
The sequence of exocrine and endocrine damage during vascularized rat pancreatic allograft rejection.
Transplant Proc. 1989 Feb;21(1 Pt 1):498-9.
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Distinct histologic patterns of acute, prolonged, and chronic rejection in vascularized rat pancreas allografts.血管化大鼠胰腺同种异体移植中急性、长期和慢性排斥反应的不同组织学模式。
Am J Pathol. 1986 Aug;124(2):253-62.
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Correlation of the arterial resistive index in pancreas transplants of patients with transplant rejection.移植排斥患者胰腺移植中动脉阻力指数的相关性
AJR Am J Roentgenol. 1997 Jun;168(6):1445-7. doi: 10.2214/ajr.168.6.9168705.
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Prevention of autoimmune recurrence and rejection by adenovirus-mediated CTLA4Ig gene transfer to the pancreatic graft in BB rat.通过腺病毒介导的CTLA4Ig基因转移至BB大鼠胰腺移植物来预防自身免疫复发和排斥反应。
Diabetes. 1999 Mar;48(3):652-7. doi: 10.2337/diabetes.48.3.652.
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Experimental pancreas allograft rejection: correlation between histologic and functional rejection and the efficacy of antirejection therapy.实验性胰腺同种异体移植排斥反应:组织学和功能性排斥反应之间的相关性以及抗排斥治疗的疗效
Surgery. 1985 Aug;98(2):330-7.

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