Stoica Loredana Elena, Dascălu Rucsandra Cristina, Pătraşcu Virgil, Ciurea Raluca Niculina, Brănişteanu Daciana Elena, Georgescu Diana Monica, Ciurea Paulina Lucia
Department of Dermatology, University of Medicine and Pharmacy of Craiova, Romania;
Rom J Morphol Embryol. 2015;56(2 Suppl):827-32.
Trichoepithelioma is part of the adnexal carcinomas. It is a benign, small tumor, usually under a centimeter in diameter, which develops in the basal cells of the hair follicle.
We present the case of a 30-year-old female patient, from rural area, which was hospitalized in the Clinic of Dermatology, Emergency County Hospital, Craiova, Romania, in March 2015, for the presence of a skin tumor, with round-oval shape, 0.5 cm in diameter, brownish colored, located on the left cervical region. The patient had no past medical history. The skin tumor appeared two years ago, and it was slowly increasing in size. Physical examination was in normal ranges. The dermatoscopic examination reveal a pearly white background covered with tumor islands that were oval shaped, with hyperpigmentation, centered by keratin cysts and surrounded by collagen. During hospitalization, we performed tumor biopsy. The histopathological examination showed microscopic structure of trichoepithelioma. After history taking, physical examination, dermatoscopic examination and histopathological result, our diagnosis was left cervical trichoepithelioma.
Trichoepithelioma is a rare trichogenic tumor, which appears at any age, including newborns, with potential for local recurrence. Our case report represents a classic dermatoscopic aspect of trichoepithelioma, that can have close resemblance to basal cell carcinoma and other skin adnexal tumors, clinically, dermatoscopic and histopathological.
毛发上皮瘤是附属器癌的一部分。它是一种良性小肿瘤,直径通常在一厘米以下,发生于毛囊的基底细胞。
我们报告一例30岁女性患者,来自农村地区,于2015年3月因左颈部出现一个直径0.5厘米、椭圆形、褐色的皮肤肿瘤入住罗马尼亚克拉约瓦县急诊医院皮肤科。患者无既往病史。该皮肤肿瘤两年前出现,且大小在缓慢增大。体格检查正常。皮肤镜检查显示珍珠白色背景上覆盖着椭圆形的肿瘤岛,有色素沉着,以角质囊肿为中心,周围有胶原蛋白。住院期间,我们进行了肿瘤活检。组织病理学检查显示为毛发上皮瘤的微观结构。经过病史采集、体格检查、皮肤镜检查和组织病理学检查结果,我们诊断为左颈部毛发上皮瘤。
毛发上皮瘤是一种罕见的毛发源性肿瘤,可发生于任何年龄,包括新生儿,有局部复发的可能。我们的病例报告展示了毛发上皮瘤典型的皮肤镜表现,在临床、皮肤镜和组织病理学方面,它可能与基底细胞癌及其他皮肤附属器肿瘤极为相似。