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经鼻颅咽管瘤手术后垂体功能的保留:病例报告及文献综述

Preservation of Pituitary Function after Endonasal Craniopharyngioma Surgery: Case Report and Review of the Literature.

作者信息

Prabhu Vishaal, Anand Vijay K, Schwartz Theodore H

机构信息

Neurological Surgery, University of Rochester Medical Center.

Otolaryngology, New York-Presbyterian/Weill Cornell Medical Center.

出版信息

Cureus. 2015 Aug 17;7(8):e305. doi: 10.7759/cureus.305.

DOI:10.7759/cureus.305
PMID:26430579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4578786/
Abstract

Craniopharyngiomas comprise approximately 3% of all intracranial tumors. Preservation of pituitary function after resection represents a significant challenge due to their location in the anterior skull base and aggressive local behavior. We report a case of a 79-year-old woman with a large suprasellar craniopharyngioma who presented with visual loss. MRI revealed a suprasellar cystic mass with mass effect on the optic chiasm and pituitary gland. Following endoscopic endonasal gross total resection of the tumor, the patient's pituitary function returned to normal.

摘要

颅咽管瘤约占所有颅内肿瘤的3%。由于其位于前颅底且具有侵袭性的局部行为,切除术后垂体功能的保留是一项重大挑战。我们报告一例79岁女性,患有巨大鞍上颅咽管瘤,表现为视力丧失。磁共振成像(MRI)显示鞍上囊性肿块,对视交叉和垂体有占位效应。经鼻内镜下肿瘤全切术后,患者垂体功能恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/1f7c35503cc6/cureus-0007-000000000305-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/a4de2ab296e8/cureus-0007-000000000305-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/967615b949ed/cureus-0007-000000000305-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/a6e4b37b4f3f/cureus-0007-000000000305-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/1f7c35503cc6/cureus-0007-000000000305-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/a4de2ab296e8/cureus-0007-000000000305-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/967615b949ed/cureus-0007-000000000305-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/a6e4b37b4f3f/cureus-0007-000000000305-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8311/4578786/1f7c35503cc6/cureus-0007-000000000305-i04.jpg

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2
The endoscopic endonasal approach for the management of craniopharyngiomas: a series of 103 patients.内镜经鼻入路治疗颅咽管瘤:103 例系列研究。
J Neurosurg. 2014 Jul;121(1):100-13. doi: 10.3171/2014.3.JNS131521. Epub 2014 May 2.
3
Endoscopic endonasal surgery for craniopharyngiomas: surgical outcome in 64 patients.
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J Neurosurg. 2013 Nov;119(5):1194-207. doi: 10.3171/2013.6.JNS122259. Epub 2013 Aug 2.
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