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一项使用不可吸收聚丙烯网进行中面部年轻化的多中心非对照临床研究:疗效与安全性评估

A Multicenter Noncomparative Clinical Study on Midface Rejuvenation Using a Nonabsorbable Polypropylene Mesh: Evaluation of Efficacy and Safety.

作者信息

Pak Chang Sik, Chang Lan Sook, Lee Hobin, Jeong Jae Hoon, Jeong Jinwook, Yoon Eul-Sik, Heo Chan Yeong

机构信息

Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Department of Plastic and Reconstructive Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.

出版信息

Arch Plast Surg. 2015 Sep;42(5):572-9. doi: 10.5999/aps.2015.42.5.572. Epub 2015 Sep 15.

DOI:10.5999/aps.2015.42.5.572
PMID:26430628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4579168/
Abstract

BACKGROUND

Facial rejuvenation can be achieved using a variety of techniques. Since minimally invasive procedures for face lifting have become popular because of their convenience and short operating time, numerous minimally invasive surgical procedures have been developed. In this study, a nonabsorbable polypropylene mesh is introduced as a new face lifting instrument, with the nasolabial fold as the main target area. In this paper, we report the efficacy and safety of a polypropylene mesh in midface rejuvenation.

METHODS

Thirty-three subjects with moderate-to-severe nasolabial folds were enrolled from two medical institutions for a noncomparative single-sample study. A mesh was inserted above the superficial muscular aponeurotic system layer, reaching the nasolabial folds through a temporal scalp incision. After 3 weeks, the temporal end of the mesh was pulled to provide a lifting effect. Then, the mesh was fixed to the deep temporal fascia using nonabsorbable sutures. To evaluate efficacy, we compared the scores on the Wrinkle Severity Rating Scale and a visual analog scale for patient satisfaction between the baseline and 7 weeks postoperatively. In addition, we evaluated safety based on the incidence of adverse events.

RESULTS

The treatment was deemed effective at improving wrinkles in 23 of 28 cases, and patient satisfaction improved significantly during the study period. There were seven cases of skin or subcutaneous tissue complications, including edema and erythema, but there were no suspected serious adverse events.

CONCLUSIONS

Face lifting using a nonabsorbable mesh can improve nasolabial folds without serious adverse effects. Thus, this technique is safe and effective for midface rejuvenation.

摘要

背景

面部年轻化可通过多种技术实现。由于微创面部提升手术因其便利性和手术时间短而受到欢迎,因此已开发出许多微创外科手术。在本研究中,一种不可吸收的聚丙烯网片被引入作为一种新的面部提升器械,以鼻唇沟为主要目标区域。在本文中,我们报告了聚丙烯网片在中面部年轻化中的疗效和安全性。

方法

从两家医疗机构招募了33名中重度鼻唇沟患者进行非对照单样本研究。将网片插入浅表肌肉腱膜系统层上方,通过颞部头皮切口到达鼻唇沟。3周后,拉动网片的颞端以提供提升效果。然后,使用不可吸收缝线将网片固定于颞深筋膜。为评估疗效,我们比较了基线时和术后7周的皱纹严重程度评分量表得分以及患者满意度视觉模拟量表得分。此外,我们根据不良事件的发生率评估安全性。

结果

28例中有23例治疗被认为对改善皱纹有效,并且在研究期间患者满意度显著提高。有7例皮肤或皮下组织并发症,包括水肿和红斑,但没有疑似严重不良事件。

结论

使用不可吸收网片进行面部提升可改善鼻唇沟且无严重不良反应。因此,该技术对于中面部年轻化是安全有效的。

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