利用超声测量胎儿胸围对致死性肺发育不全进行产前预测。
Prenatal prediction of lethal pulmonary hypoplasia using ultrasonic fetal chest circumference.
作者信息
Songster G S, Gray D L, Crane J P
机构信息
Department of Obstetrics and Gynecology, Jewish Hospital, St. Louis, Missouri.
出版信息
Obstet Gynecol. 1989 Feb;73(2):261-6.
Ultrasonic measurement of fetal chest circumference was tested as a predictor of pulmonary hypoplasia in a group of 26 fetuses at known risk. A 42% prevalence of autopsy-proved pulmonary hypoplasia was found in this population. Chest circumference measurements were plotted on published nomograms based upon head circumference, femur length, and gestational age. Longitudinal observations revealed a progressive lag in chest circumference growth among fetuses who proved to have pulmonary hypoplasia. The nomogram based on femur length provided sensitivity, specificity, and normal and abnormal predictive values of 80, 92, 92, and 89%, respectively. The results of this investigation suggest that fetal chest circumference measurement is a useful adjunct in establishing the diagnosis of lethal pulmonary hypoplasia.
在一组26例已知有风险的胎儿中，对超声测量胎儿胸围作为肺发育不全预测指标进行了测试。在这一群体中，经尸检证实的肺发育不全患病率为42%。根据头围、股骨长度和孕周，将胸围测量值绘制在已发表的列线图上。纵向观察显示，经证实有肺发育不全的胎儿胸围生长逐渐滞后。基于股骨长度的列线图的敏感性、特异性、正常和异常预测值分别为80%、92%、92%和89%。本研究结果表明，胎儿胸围测量在确诊致死性肺发育不全方面是一项有用的辅助手段。
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