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经皮注射纤维蛋白胶修复一名2岁儿童的创伤性蛛网膜下腔 - 胸膜瘘

Repair of a traumatic subarachnoid-pleural fistula with the percutaneous injection of fibrin glue in a 2-year-old.

作者信息

Chu Jason K, Miller Brandon A, Bazylewicz Michael P, Holbrook John F, Chern Joshua J

机构信息

Departments of 1 Neurosurgery and.

Radiology, Emory University School of Medicine, Atlanta; and.

出版信息

J Neurosurg Pediatr. 2016 Jan;17(1):13-8. doi: 10.3171/2015.5.PEDS15194. Epub 2015 Oct 2.

Abstract

Subarachnoid-pleural fistulas (SPFs) are rare clinical entities that occur after severe thoracic trauma or iatrogenic injury during anterolateral approaches to the spine. Treatment of these fistulas often entails open repair of the dural defect. The authors present the case of an SPF in a 2-year-old female after a penetrating injury to the chest. The diagnosis of an SPF was suspected given the high chest tube output and was confirmed with a positive β2-transferrin test of the chest tube fluid, as well as visualization of dural defects on MRI. The dural defects were successfully repaired with CT-guided percutaneous epidural injection of fibrin glue alone. This case represents the youngest pediatric patient with a traumatic SPF to be treated percutaneously. This technique can be safely used in pediatric patients, offers several advantages over open surgical repair, and could be considered as an alternative first-line therapy for the obliteration of SPFs.

摘要

蛛网膜-胸膜瘘(SPF)是一种罕见的临床病症,发生于严重胸部创伤或脊柱前外侧入路手术的医源性损伤之后。治疗这些瘘管通常需要对硬脊膜缺损进行开放性修复。作者报告了一名2岁女性在胸部穿透伤后发生SPF的病例。鉴于胸腔闭式引流管引流量大,怀疑为SPF,并通过胸腔闭式引流管液体的β2-转铁蛋白检测阳性以及MRI上硬脊膜缺损的可视化得以确诊。仅通过CT引导下经皮硬膜外注射纤维蛋白胶就成功修复了硬脊膜缺损。该病例是接受经皮治疗的最年幼的创伤性SPF儿科患者。这项技术可安全用于儿科患者,与开放性手术修复相比具有多个优点,可被视为封堵SPF的替代一线治疗方法。

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