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代谢纠正作为改善2型糖尿病管理的一种工具。

Metabolic Correction as a tool to improve diabetes type 2 management.

作者信息

Miranda-Massari Jorge R, Gonzalez Michael J, Fernando Alvarez-Soto, Cidre Carlos, Paz Iván M, Charvel Jorge, Martínez Viridiana, Duconge Jorge, Aponte Aileen, Ricart Carlos M

出版信息

Bol Asoc Med P R. 2015 Apr-Jun;107(2):54-9.

Abstract

Diabetes Mellitus type 2 (DM2) is a metabolic disease that develops by a decrease in sensitivity of insulin receptors as an effect of the disruption certain metabolic functions in the processing of glucose. DM2 patients have, uncontrolled glucose levels, and commonly have problems with obesity and cardiovascular disease. Patients are treated with standard diet, insulin, diabetic oral agents and antihypertensive drugs, but this approach does not completely stops tissue deterioration since it does not address the metabolic root of the disease. Metabolic correction is proposed as a suitable adjunct treatment to improve clinical outcomes. Metabolic correction is based on diet modification, proper hydration and scientific supplementation directed to improve cellular biochemistry and metabolic efficiency. In addition, other possible benefits may include reduction in medication use, disease complications and medical costs. To test the results of a metabolic correction program, 25 patients with DM2 participated in an education program about adequate food consumption that promoted control of blood glucose levels. Anthropometric measurements and blood tests were performed during a 13 week program based on a low carbohydrate diet, proper hydration and magnesium supplementation. The metabolic correction program implemented by a proprietary educational system resulted in significant reductions in glucose, triglycerides, cholesterol, weight and waist circumference. Improvements in these values could represent an important reduction of coronary heart disease risk factors as well as other chronic degenerative diseases. In addition there was medication dosage reduction in one or more medications in 21 of the 25 participating patients, which suggest that the program has the potential to improve health outcomes and reduce health care costs.

摘要

2型糖尿病(DM2)是一种代谢性疾病,由于葡萄糖代谢过程中某些代谢功能紊乱,导致胰岛素受体敏感性降低而发病。DM2患者血糖水平失控,通常伴有肥胖和心血管疾病问题。患者接受标准饮食、胰岛素、糖尿病口服药物和抗高血压药物治疗,但这种方法并不能完全阻止组织恶化,因为它没有解决疾病的代谢根源。代谢纠正被提议作为一种合适的辅助治疗方法来改善临床结果。代谢纠正基于饮食调整、适当补水和科学补充营养,旨在改善细胞生物化学和代谢效率。此外,其他可能的益处可能包括减少药物使用、疾病并发症和医疗费用。为了测试代谢纠正计划的效果,25名DM2患者参加了一个关于合理饮食摄入的教育计划,该计划促进了血糖水平的控制。在一个基于低碳水化合物饮食、适当补水和补充镁的为期13周的计划中,进行了人体测量和血液检测。由一个专有的教育系统实施的代谢纠正计划导致葡萄糖、甘油三酯、胆固醇、体重和腰围显著降低。这些数值的改善可能意味着冠心病风险因素以及其他慢性退行性疾病的重要降低。此外,25名参与患者中有21名患者的一种或多种药物剂量减少,这表明该计划有可能改善健康结果并降低医疗成本。

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