Erol Bülent, Onay Tolga, Çalışkan Emrah, Okay Erhan
Acta Orthop Belg. 2015 Sep;81(3):530-7.
The objective of this retrospective study was to evaluate clinical outcomes, local recurrence and complication rates of antihelminthic chemotherapy and wide resection in patients with muscle or bone hydatidosis. The authors treated 10 patients (6 females, 4 males) between 2004 and 2012: 8 with muscle and 2 with bone hydatidosis. The mean age at surgery was 42.5 years (range, 11-66 years). All patients were treated with wide resection and pre- and postoperative chemotherapy with albendazole. The mean follow-up was 64 months (range, 28-120 months). All patients achieved satisfactory clinical outcomes. There were no local recurrences. Surgical complications were seen in 3 patients (30%) : one superficial infection, one deep infection, and one hematoma. Two (20%) required additional surgery. An aggressive oncological approach, consisting of antihelminthic chemotherapy and wide resection, can provide favorable clinical outcomes and prevent local recurrence in patients with musculoskeletal hydatidosis. Potential complications of aggressive surgery should be preferred to potential morbidity of local and systemic dissemination.
这项回顾性研究的目的是评估抗蠕虫化疗联合广泛切除治疗肌肉或骨包虫病患者的临床疗效、局部复发率和并发症发生率。作者在2004年至2012年间治疗了10例患者（6例女性，4例男性）：8例为肌肉包虫病，2例为骨包虫病。手术时的平均年龄为42.5岁（范围11 - 66岁）。所有患者均接受了广泛切除，并在术前和术后使用阿苯达唑进行化疗。平均随访时间为64个月（范围28 - 120个月）。所有患者均取得了满意的临床疗效。无局部复发情况。3例患者（30%）出现手术并发症：1例表浅感染，1例深部感染，1例血肿。2例（20%）需要再次手术。一种积极的肿瘤学治疗方法，包括抗蠕虫化疗和广泛切除，可以为肌肉骨骼包虫病患者提供良好的临床疗效并预防局部复发。与局部和全身播散的潜在发病率相比，积极手术的潜在并发症应更为可取。
