Cano-García María Del Carmen, Casares-Pérez Rosario, Castillo-Gallardo Elisabeth, Merino-Salas Sergio, Arrabal-Martín Miguel, Arrabal-Polo Miguel Ángel
Rev Med Chil. 2015 Aug;143(8):1001-4. doi: 10.4067/S0034-98872015000800006.
Flexible cystoscopy is a common test in clinical practice done with or without antibiotic prophylaxis.
To evaluate the efficacy of antibiotic prophylaxis with ciprofloxacin to reduce the incidence of urinary infection.
Prospective, non-randomized observational study that included 60 patients divided into two groups. Group 1 received prophylactic ciprofloxacin 500 mg, one hour prior to the procedure and group 2 did not receive prophylaxis. The presence of bacteriuria, symptoms or signs of urinary infection or attending Emergency rooms or primary care for these symptoms were recorded during the seven days after the cystoscopy.
In groups 1 and 2, four and one patients had a positive urine culture, respectively. Only one patient in group 1 consulted in primary care for symptoms. No significant differences in symptoms or signs of urinary infection between groups were observed.
In this group of patients, antibiotic prophylaxis with ciprofloxacin 500 mg prior to cystoscopy had no benefit.
软性膀胱镜检查是临床实践中一种常见的检查，检查时可使用或不使用抗生素预防。
评估环丙沙星抗生素预防措施降低尿路感染发生率的疗效。
前瞻性、非随机观察性研究，纳入60例患者，分为两组。第1组在检查前1小时接受500毫克环丙沙星预防性治疗，第2组未接受预防性治疗。在膀胱镜检查后的七天内，记录是否存在菌尿、尿路感染的症状或体征，或因这些症状前往急诊室或初级保健机构就诊的情况。
第1组和第2组分别有4例和1例患者尿培养呈阳性。第1组中只有1例患者因症状到初级保健机构就诊。两组之间在尿路感染的症状或体征方面未观察到显著差异。
在这组患者中，膀胱镜检查前使用500毫克环丙沙星进行抗生素预防并无益处。
