Conrad M E
Division of Hematology and Oncology, University of South Alabama, Mobile.
Am J Med Sci. 1989 Jan;297(1):35-7. doi: 10.1097/00000441-198901000-00008.
During the past two years, sporadic cases of a rickettsial-like illness were reported in humans living in the Southeastern United States. The illness was serologically similar to Ehrlichia canis infections in dogs. It resembled spotless Rocky Mountain Spotted Fever but was differentiated from this infection serologically with acute and convalescent sera showing increasing titers to Ehrlichia canis. E. canis infection should be suspected in patients with fever, headache, malaise, myalgia, gastrointestinal symptoms, relative bradycardia, leukopenia, thrombocytopenia, and a recent exposure to either dogs or ticks. Although recovery has been observed in humans without treatment, prompt therapy with tetracycline is advised before obtaining results of serologic studies because an immunologically similar illness in untreated dogs has been lethal.
在过去两年中，美国东南部有居民报告出现了类似立克次氏体病的散发病例。该疾病在血清学上与犬埃立克体感染相似。它类似无疹型落基山斑疹热，但通过急性期和恢复期血清对犬埃立克体的滴度升高在血清学上与这种感染相区分。对于出现发热、头痛、不适、肌痛、胃肠道症状、相对心动过缓、白细胞减少、血小板减少且近期接触过狗或蜱的患者，应怀疑感染犬埃立克体。尽管未治疗的患者也有康复的情况，但在获得血清学研究结果之前，建议立即用四环素进行治疗，因为未经治疗的犬类中与免疫相似的疾病是致命的。
