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表现为软组织肿瘤的头皮放线菌病:一例报告并文献复习

Scalp actinomycosis presenting as soft tissue tumour: A case report with literature review.

作者信息

Akhtar Murtaza, Zade Manish P, Shahane Pawan L, Bangde Akshay P, Soitkar Sagar M

机构信息

Dept. of Surgery, NKP Salve Institute Of Medical Sciences, Digdoh Hills, Hingna Road, Nagpur 440019, India.

Dept. of Plastic Surgery, NKP Salve Institute Of Medical Sciences, Digdoh Hills, Hingna Road, Nagpur 440019, India.

出版信息

Int J Surg Case Rep. 2015;16:99-101. doi: 10.1016/j.ijscr.2015.09.030. Epub 2015 Sep 28.

Abstract

INTRODUCTION

Actinomycosis is a rare subacute or chronic bacterial infection caused by Gram positive, anaerobic or microaerophilic bacilli. It is characterized by suppuration, abscess formation, tissue fibrosis, draining sinuses & rarely as a soft tissue mass mimicking a tumor.

CASE REPORT

A 16 year old boy sustained a trauma over right forehead & wound after which patient presented with swelling over right forehead which was excised and was histopathologically reported as angiomatous lesion. Patient presented with recurrent swelling with ulceration over the same site. CT scan showed soft tissue mass with periosteal reaction of right frontal bone. Wide local excision with removal of periosteum was carried out. Raw area was covered with rotational scalp flap. Histopathology of the excised specimen showed features of actinomycosis.

DISCUSSION

Cutaneous actinomycosis presenting as pseudocarcinomatous or sarcomatous mass is rare. Trauma is a common preceding event which was observed in present case. Histopathological confirmation is mandatory with visualization of sulfur granules. It is managed by high dose IV antibiotics. Surgical resection is a useful adjuvant therapy specially in large, disfiguring masses not responding to medical treatment and where excisional biopsy is helpful in establishing the diagnosis surgical excision alone is not curative, post operative long term antibiotics are adjuvant therapy to avoid recurrence.

CONCLUSION

Actinomycosis of scalp skin is a rare entity and tumor like presentation is still uncommon. Lesions not resolving with routine antibiotics therapy should be suspected clinically as actinomycosis and treated with high dose antibiotics as histopathology from small biopsy is unreliable.

摘要

引言

放线菌病是一种由革兰氏阳性、厌氧或微需氧杆菌引起的罕见亚急性或慢性细菌感染。其特征为化脓、脓肿形成、组织纤维化、引流窦道,很少表现为类似肿瘤的软组织肿块。

病例报告

一名16岁男孩右前额部受伤并出现伤口,之后患者右前额部出现肿胀,肿胀部位被切除,组织病理学报告为血管瘤样病变。患者同一部位反复出现肿胀并伴有溃疡。CT扫描显示右额骨有软组织肿块及骨膜反应。进行了广泛局部切除并去除骨膜。创面包覆旋转头皮瓣。切除标本的组织病理学显示放线菌病特征。

讨论

表现为假癌性或肉瘤样肿块的皮肤放线菌病罕见。创伤是常见的前驱事件,本病例即观察到这一点。必须通过观察硫磺颗粒进行组织病理学确诊。治疗采用大剂量静脉用抗生素。手术切除是一种有用的辅助治疗,特别是对于大的、毁容性肿块且对药物治疗无反应的情况,以及切除活检有助于确诊的情况,单独手术切除不能治愈,术后长期使用抗生素作为辅助治疗以避免复发。

结论

头皮皮肤放线菌病是一种罕见疾病,肿瘤样表现仍然不常见。临床上对于常规抗生素治疗无效的病变应怀疑为放线菌病,并使用大剂量抗生素治疗,因为小活检的组织病理学结果不可靠。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8797/4643463/f88d138fa67b/gr1.jpg

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