Reay Alan J, Fairlamb Ian J S
Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Chem Commun (Camb). 2015 Nov 25;51(91):16289-307. doi: 10.1039/c5cc06980g.
This feature article examines the potential of heterogeneous Pd species to mediate catalytic C-H bond functionalisation processes employing suitable substrates (e.g. aromatic/heteroaromatic compounds). A focus is placed on the reactivity of supported and non-supported Pd nanoparticle (PdNPs) catalysts, in addition to the re-appropriation of well-established heterogeneous Pd catalysts such as Pd/C. Where possible, reasonable comparisons are made between PdNPs and traditional 'homogeneous' Pd precatalyst sources (which form PdNPs). The involvement of higher order Pd species in traditional cross-coupling processes, such as Mizoroki-Heck, Sonogashira and Suzuki-Miyaura reactions, allows the exemplification of potential future topics for study in the area of catalytic C-H bond functionalisation processes.
这篇专题文章探讨了多相钯物种利用合适底物（如芳香族/杂芳香族化合物）介导催化C-H键官能化过程的潜力。除了重新利用成熟的多相钯催化剂（如Pd/C）外，还重点研究了负载型和非负载型钯纳米颗粒（PdNPs）催化剂的反应活性。在可能的情况下，对PdNPs与传统的“均相”钯预催化剂源（形成PdNPs）进行了合理比较。高阶钯物种参与传统的交叉偶联过程，如 Mizoroki-Heck、Sonogashira 和 Suzuki-Miyaura 反应，这为催化C-H键官能化过程领域未来潜在的研究课题提供了例证。
