Floege J
Klinik für Nieren- und Hochdruckkrankheiten, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52057, Aachen, Deutschland.
Internist (Berl). 2015 Nov;56(11):1277-85; quiz 1286-7. doi: 10.1007/s00108-015-3781-1.
Many forms of glomerulonephritis, even the more common types belong to the so-called rare diseases; however, they are very important, for example with respect to health economics as they often affect young people. An example is immunoglobulin A (IgA) nephropathy, which is the most common cause of end stage renal disease in young adults. This review summarizes the current knowledge on the pathogenesis, clinical presentation and therapy of the most common European types of glomerulonephritis with a special focus on the most recently acquired knowledge on IgA nephropathy, membranous glomerulonephritis, minimal change nephropathy and focal segmental glomerulosclerosis (FSGS).
许多形式的肾小球肾炎,即使是较为常见的类型也属于所谓的罕见病;然而,它们非常重要,例如从卫生经济学角度来看,因为它们常常影响年轻人。一个例子是免疫球蛋白A(IgA)肾病,它是年轻成年人终末期肾病的最常见病因。本综述总结了欧洲最常见类型肾小球肾炎的发病机制、临床表现和治疗方面的现有知识,特别关注了IgA肾病、膜性肾小球肾炎、微小病变肾病和局灶节段性肾小球硬化(FSGS)的最新知识。