Benson Max M, Frishman William H
From the *Departments of Medicine, New York Methodist Hospital, Brooklyn, New York; and †New York Medical College/Westchester Medical Center, Valhalla, New York.
Cardiol Rev. 2015 Nov-Dec;23(6):312-6. doi: 10.1097/CRD.0000000000000048.
Psoriasis is a common, chronic, autoimmune condition characterized by excessive growth and differentiation of keratinocytes that affects approximately 1% to 3% of the general population in the United States. Mounting evidence has led to an increasing awareness that psoriasis as a disease is more than "skin deep" and that it shares systemic manifestations with other chronic inflammatory diseases such as Crohn's and diabetes mellitus. Recent studies have not only shown an increased prevalence of cardiovascular risk factors in psoriasis but have also identified psoriasis as an independent risk factor for developing cardiovascular disease. This calls for an approach beyond managing traditional risk factors, which remain the standard guidelines at present.
银屑病是一种常见的慢性自身免疫性疾病，其特征为角质形成细胞过度增殖和分化，在美国约1%至3%的普通人群中受到影响。越来越多的证据表明，银屑病作为一种疾病，其影响不仅限于皮肤表面，还与其他慢性炎症性疾病如克罗恩病和糖尿病有共同的全身表现。最近的研究不仅表明银屑病患者心血管危险因素的患病率增加，还将银屑病确定为发生心血管疾病的独立危险因素。这就需要一种超越管理传统危险因素的方法，而传统危险因素目前仍是标准指南。
