Torres-Coy J A, Rodríguez-Castillo B A, Pérez-Alfonzo R, DE Waard J H
Laboratorio de Tuberculosis,Servicio Autónomo Instituto de Biomedicina 'Dr. Jacinto Convit',Caracas,Venezuela.
Facultad de Medicina,Universidad Central de Venezuela,Caracas,Venezuela.
Epidemiol Infect. 2016 Apr;144(5):1117-20. doi: 10.1017/S0950268815002381. Epub 2015 Oct 6.
Outbreaks of soft tissue or skin infection due to non-tuberculous mycobacteria are reported frequently in scientific journals but in general the infection source in these outbreaks remains unknown. In Venezuela, in two distinct outbreaks, one after breast augmentation surgery and another after hydrolipoclasy therapy, 16 patients contracted a soft tissue infection due to Mycobacterium abscessus subsp. abscessus. Searching for the possible environmental infection sources in these outbreaks, initially the tap water (in the hydrolipoclasy therapy outbreak) and a surgical skin marker (in the breast implant surgery outbreak), were identified as the infection sources. Molecular typing of the strains with a variable number tandem repeat typing assay confirmed the tap water as the infection source but the molecular typing technique excluded the skin marker. We discuss the results and make a call for the implementation of stringent hygiene and disinfection guidelines for cosmetic procedures in Venezuela.
非结核分枝杆菌引起的软组织或皮肤感染暴发在科学期刊中常有报道，但总体而言，这些暴发中的感染源仍不明确。在委内瑞拉，发生了两起不同的暴发事件，一起在隆胸手术后，另一起在脂肪水解疗法后，16名患者因脓肿分枝杆菌脓肿亚种感染了软组织。为寻找这些暴发中可能的环境感染源，最初确定自来水（在脂肪水解疗法暴发事件中）和一种手术皮肤标记物（在隆胸手术暴发事件中）为感染源。采用可变数目串联重复分型分析法对菌株进行分子分型，证实自来水是感染源，但分子分型技术排除了皮肤标记物。我们讨论了这些结果，并呼吁在委内瑞拉实施严格的美容手术卫生和消毒指南。
