Magruder Kathryn, Serpi Tracey, Kimerling Rachel, Kilbourne Amy M, Collins Joseph F, Cypel Yasmin, Frayne Susan M, Furey Joan, Huang Grant D, Gleason Theresa, Reinhard Matthew J, Spiro Avron, Kang Han
Mental Health Service, Ralph H. Johnson Veterans Affairs (VA) Medical Center, Charleston, South Carolina2Department of Psychiatry, Medical University of South Carolina, Charleston.
Cooperative Studies Program Coordinating Center, VA Maryland Health Care System, Perry Point.
JAMA Psychiatry. 2015 Nov;72(11):1127-34. doi: 10.1001/jamapsychiatry.2015.1786.
Many Vietnam-era women veterans served in or near war zones and may have experienced stressful or traumatic events during their service. Although posttraumatic stress disorder (PTSD) is well studied among men who served in Vietnam, no major epidemiologic investigation of PTSD among women has been performed.
To assess (1) the onset and prevalence of lifetime and current PTSD for women who served during the Vietnam era, stratified by wartime location (Vietnam, near Vietnam, or the United States), and (2) the extent to which wartime location was associated with PTSD, with adjustment for demographics, service characteristics, and wartime exposures.
DESIGN, SETTING, AND PARTICIPANTS: Survey of 8742 women who were active-duty military personnel in the US Armed Forces at any time from July 4, 1965, through March 28, 1973, and alive as of survey receipt as part of Department of Veterans Affairs Cooperative Study 579, HealthVIEWS. Data were obtained from mailed and telephone surveys from May 16, 2011, through August 5, 2012, and analyzed from June 26, 2013, through July 30, 2015.
Lifetime and current PTSD as measured by the PTSD module of the Composite International Diagnostic Interview, version 3.0; onset of PTSD; and wartime experiences as measured by the Women's Wartime Exposure Scale-Revised.
Among the 4219 women (48.3%) who completed the survey and a telephone interview, the weighted prevalence (95% CI) of lifetime PTSD was 20.1% (18.3%-21.8%), 11.5% (9.1%-13.9%), and 14.1% (12.4%-15.8%) for the Vietnam, near-Vietnam, and US cohorts, respectively. The weighted prevalence (95% CI) of current PTSD was 15.9% (14.3%-17.5%), 8.1% (6.0%-10.2%), and 9.1% (7.7%-10.5%) for the 3 cohorts, respectively. Few cases of PTSD among the Vietnam or near-Vietnam cohorts were attributable to premilitary onset (weighted prevalence, 2.9% [95% CI, 2.2%-3.7%] and 2.9% [95% CI, 1.7%-4.2%], respectively). Unadjusted models for lifetime and current PTSD indicated that women who served in Vietnam were more likely to meet PTSD criteria than women who mainly served in the United States (odds ratio [OR] for lifetime PTSD, 1.53 [95% CI, 1.28-1.83]; OR for current PTSD, 1.89 [95% CI, 1.53-2.33]). When we adjusted for wartime exposures, serving in Vietnam or near Vietnam did not increase the odds of having current PTSD (adjusted ORs, 1.05 [95% CI, 0.75-1.46] and 0.77 [95% CI, 0.52-1.14], respectively).
The prevalence of PTSD for the Vietnam cohort was higher than previously documented. Vietnam service significantly increased the odds of PTSD relative to US service; this effect appears to be associated with wartime exposures, especially sexual discrimination or harassment and job performance pressures. Results suggest long-lasting mental health effects of Vietnam-era service among women veterans.
许多越战时期的女性退伍军人曾在战区或其附近服役,服役期间可能经历过压力大或创伤性事件。虽然创伤后应激障碍(PTSD)在越战服役男性中已有充分研究,但尚未对女性进行过重大的PTSD流行病学调查。
评估(1)按战时地点(越南、越南附近或美国)分层的越战时期服役女性一生中及当前PTSD的发病情况和患病率,以及(2)战时地点与PTSD的关联程度,并对人口统计学、服役特征和战时暴露因素进行调整。
设计、背景和参与者:对1965年7月4日至1973年3月28日期间在美国武装部队中任现役军人且截至调查收到时仍在世的8742名女性进行调查,这是退伍军人事务部合作研究579(HealthVIEWS)的一部分。数据通过2011年5月16日至2012年8月5日的邮寄和电话调查获取,并于2013年6月26日至2015年7月30日进行分析。
采用综合国际诊断访谈第3.0版的PTSD模块测量一生中及当前的PTSD;PTSD的发病情况;以及采用修订后的女性战时暴露量表测量战时经历。
在完成调查和电话访谈的4219名女性(48.3%)中,越南、越南附近和美国队列中一生中PTSD的加权患病率(95%CI)分别为20.1%(18.3%-21.8%)、11.5%(9.1%-13.9%)和14.1%(12.4%-15.8%)。3个队列中当前PTSD的加权患病率(95%CI)分别为15.9%(14.3%-17.5%)、8.1%(6.0%-10.2%)和9.1%(7.7%-10.5%)。越南或越南附近队列中很少有PTSD病例可归因于入伍前发病(加权患病率分别为2.9%[95%CI,2.2%-3.7%]和2.9%[95%CI,1.7%-4.2%])。一生中及当前PTSD的未调整模型表明,在越南服役的女性比主要在美国服役的女性更有可能符合PTSD标准(一生中PTSD的优势比[OR]为1.53[95%CI,1.28-1.83];当前PTSD的OR为1.89[95%CI,1.53-2.33])。当我们对战时暴露因素进行调整后,在越南或越南附近服役并未增加当前患PTSD的几率(调整后的OR分别为1.05[95%CI,0.75-1.46]和0.77[95%CI,0.52-1.14])。
越南队列中PTSD的患病率高于先前记录。与在美国服役相比,在越南服役显著增加了患PTSD的几率;这种影响似乎与战时暴露有关,尤其是性别歧视或骚扰以及工作绩效压力。结果表明越战时期服役对女性退伍军人的心理健康有长期影响。