Kopp U C
University of Iowa College of Medicine, Iowa City.
Miner Electrolyte Metab. 1989;15(1-2):66-73.
The renorenal reflex responses to physiological stimulation of the afferent renal nerves are species-dependent. In dogs, renal mechanoreceptor (MR) stimulation results in a contralateral excitatory renorenal reflex response with a fall in contralateral renal blood flow and urinary sodium excretion at unchanged mean arterial pressure. In cats, renal MR stimulation increases mean arterial pressure and produces variable effects on contralateral renal excretion. In rats, renal MR stimulation results in a contralateral inhibitory renorenal reflex response with contralateral diuresis and natriuresis at unchanged systemic and contralateral renal hemodynamics. Renal chemoreceptor (CR) stimulation produces similar results. In spontaneously hypertensive rats renal MR and CR stimulation fails to produce a renorenal reflex response.
肾肾反射对肾传入神经生理刺激的反应具有种属依赖性。在犬类中，肾机械感受器（MR）刺激会导致对侧兴奋性肾肾反射反应，在平均动脉压不变的情况下，对侧肾血流量和尿钠排泄量下降。在猫中，肾MR刺激会升高平均动脉压，并对对侧肾排泄产生不同影响。在大鼠中，肾MR刺激会导致对侧抑制性肾肾反射反应，在全身和对侧肾血流动力学不变的情况下，出现对侧利尿和利钠。肾化学感受器（CR）刺激产生类似结果。在自发性高血压大鼠中，肾MR和CR刺激未能产生肾肾反射反应。
