Paradisi F, de Crescenzo G, Ruffilli M P
Università di Firenze, Istituto di Malattie Infettive.
Minerva Med. 1989 Jan;80(1):43-51.
In this multicenter study the authors evaluated the clinical and microbiological efficacy and the local and general safety of cefoperazone sodium in 1,546 patients (946 males and 600 females, mean age 61.3 years) with lower respiratory tract (1,044) and urinary tract (539) infections. Results were very encouraging with 95.3% of clinical cures or improvement, 91.6% of microbiological eradication, and a local and general safety which was always extremely high, i.e. 96.9% and 98.3% respectively.
在这项多中心研究中,作者评估了头孢哌酮钠对1546例(946例男性和600例女性,平均年龄61.3岁)患有下呼吸道感染(1044例)和尿路感染(539例)患者的临床和微生物学疗效以及局部和全身安全性。结果非常令人鼓舞,临床治愈率或改善率为95.3%,微生物清除率为91.6%,局部和全身安全性一直极高,分别为96.9%和98.3%。