Dunnihoo D R, Otterson W N, Mailhes J B, Lewis D F, Grafton W D, Brown C C
Department of Obstetrics and Gynecology, Louisiana State University Medical Center, Shreveport.
Obstet Gynecol. 1989 Mar;73(3 Pt 1):390-4.
Cesarean sections were performed on 30 rabbits at term pregnancy. Two incisions were made in each of the two uterine horns, and each incision was closed according to a predetermined method (continuous, everted; continuous, inverted; interrupted, everted; or interrupted, inverted). Tissue from the uterine scar region was sampled at three different time periods (5-8 days, 12-15 days, or 28-30 days) post-surgery to evaluate the degree of uterine healing by a variety of histologic criteria. The initial healing response in the scarred region occurred around 28-30 days post-surgery. The different uterine closure techniques did not appreciably influence the healing response in this study. We evaluated tensile strength in 36 uterine muscle specimens containing the scar obtained from nine animals in the 28-32-days post-surgery group. Of these 36 specimens, 86.1% tore through the muscle instead of through the scar when tension was applied to the muscle.
对30只足月妊娠的兔子进行剖宫产。在两个子宫角的每一个上做两个切口，每个切口按照预定方法（连续外翻；连续内翻；间断外翻；或间断内翻）进行缝合。在术后三个不同时间段（5 - 8天、12 - 15天或28 - 30天）采集子宫瘢痕区域的组织，通过多种组织学标准评估子宫愈合程度。瘢痕区域的初始愈合反应发生在术后约28 - 30天。在本研究中，不同的子宫缝合技术对愈合反应没有明显影响。我们评估了术后28 - 32天组中9只动物的36个含瘢痕的子宫肌肉标本的抗张强度。在这36个标本中，当对肌肉施加张力时，86.1%的标本是在肌肉处撕裂，而非在瘢痕处。
