Payabvash Seyedmehdi, Meric Kaan, Cayci Zuzan
Department of Radiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Department of Radiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Clin Imaging. 2016 Jan-Feb;40(1):101-5. doi: 10.1016/j.clinimag.2015.09.001. Epub 2015 Sep 4.
To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer.
In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included.
Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<.001) and short-axis diameter (P=.015) compared to benign nodes. An SUV-max of ≥2.5 was 100% sensitive, and an SUV-max ≥5.5 was 100% specific for malignant lymphadenopathy.
The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.
鉴别头颈部癌患者颈部淋巴结的良恶性。
在这项回顾性研究中，纳入了39例接受正电子发射断层扫描（PET）/计算机断层扫描（CT）及图像引导下淋巴结活检的原发性头颈部癌患者。
总体而言，23例（59%）患者经活检证实有恶性颈部淋巴结病。与良性淋巴结相比，恶性淋巴结的最大标准化摄取值（SUV-max）更高（P<0.001），短轴直径更大（P=0.015）。SUV-max≥2.5对恶性淋巴结病的敏感性为100%，SUV-max≥5.5对恶性淋巴结病的特异性为100%。
PET/CT的SUV-max值有助于鉴别头颈部癌患者颈部恶性淋巴结。
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