使用全身治疗方法来管理局灶性多汗症。
Use of Systemic Therapies to Manage Focal Hyperhidrosis.
作者信息
Glaser Dee Anna, Glaser Katherine
出版信息
Mo Med. 2015 Jul-Aug;112(4):287-91.
Abstract
Primary hyperhidrosis (excessive sweating) commonly affects the axillae, palms, soles, scalp, face, and the groin. Patients may have multiple areas involved making localized therapy challenging. Systemic therapy may be necessary and can be used as monotherapy or combined with other hyperhidrosis treatments for optimal outcomes. Systemic therapy can also be used to treat secondary hyperhidrosis and compensatory hyperhidrosis. Patient selection and counseling are key, and monitoring for side effects is required throughout therapy.
摘要
原发性多汗症（出汗过多）通常影响腋窝、手掌、脚底、头皮、面部和腹股沟。患者可能有多个部位受累，这使得局部治疗具有挑战性。全身治疗可能是必要的，可作为单一疗法使用，或与其他多汗症治疗方法联合使用以获得最佳效果。全身治疗也可用于治疗继发性多汗症和代偿性多汗症。患者的选择和咨询是关键，并且在整个治疗过程中都需要监测副作用。
相似文献
1
Use of Systemic Therapies to Manage Focal Hyperhidrosis.
Mo Med. 2015 Jul-Aug;112(4):287-91.
2
Oral medications.
Dermatol Clin. 2014 Oct;32(4):527-32. doi: 10.1016/j.det.2014.06.002. Epub 2014 Jul 29.
3
Hyperhidrosis: Management Options.
Am Fam Physician. 2018 Jun 1;97(11):729-734.
4
Oxybutynin as an alternative treatment for hyperhidrosis.
An Bras Dermatol. 2017 Mar-Apr;92(2):217-220. doi: 10.1590/abd1806-4841.201755126.
5
Glycopyrronium Tosylate (Qbrexza) for Hyperhidrosis.
Skin Therapy Lett. 2019 Mar;24(2):1-3.
6
Systemic treatment of hyperhidrosis.
Actas Dermosifiliogr. 2015 May;106(4):271-7. doi: 10.1016/j.ad.2014.11.012. Epub 2015 Jan 28.
7
Glycopyrrolate-induced craniofacial compensatory hyperhidrosis successfully treated with oxybutynin: report of a novel adverse effect and subsequent successful treatment.
Dermatol Online J. 2016 Oct 15;22(10):13030/qt4wp1g44b.
8
Topical therapies in hyperhidrosis care.
Dermatol Clin. 2014 Oct;32(4):485-90. doi: 10.1016/j.det.2014.06.008. Epub 2014 Jul 29.
9
Topical glycopyrrolate for patients with facial hyperhidrosis.
Br J Dermatol. 2008 May;158(5):1094-7. doi: 10.1111/j.1365-2133.2008.08476.x. Epub 2008 Feb 22.
10
Botulinum toxin for hyperhidrosis of areas other than the axillae and palms/soles.
Dermatol Clin. 2014 Oct;32(4):517-25. doi: 10.1016/j.det.2014.06.001. Epub 2014 Jul 28.
引用本文的文献
1
Exploring New and Potential Indications for Botulinum Toxin Treatment: An Updated Literature Review.
Cureus. 2024 Dec 11;16(12):e75549. doi: 10.7759/cureus.75549. eCollection 2024 Dec.
2
Gap junction-mediated contraction of myoepithelial cells induces the peristaltic transport of sweat in human eccrine glands.
Commun Biol. 2023 Nov 18;6(1):1175. doi: 10.1038/s42003-023-05557-9.
本文引用的文献
1
Hyperhidrosis: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins.
Toxins (Basel). 2013 Apr 23;5(4):821-40. doi: 10.3390/toxins5040821.
2
Effectiveness of oxybutynin for treatment of hyperhidrosis in overweight and obese patients.
Rev Assoc Med Bras (1992). 2013 Mar-Apr;59(2):143-7. doi: 10.1016/j.ramb.2012.11.002.
3
Glycopyrrolate for antidepressant-associated excessive sweating.
J Clin Psychopharmacol. 2013 Apr;33(2):279-80. doi: 10.1097/JCP.0b013e31828567f2.
4
Oxybutynin treatment for hyperhidrosis: a comparative analysis between genders.
Einstein (Sao Paulo). 2012 Oct-Dec;10(4):405-8. doi: 10.1590/s1679-45082012000400002.
5
[Use of oral oxybutynin at 7.5 mg per day in primary hyperhidrosis].
Rev Med Liege. 2012 Oct;67(10):520-6.
6
Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial.
J Eur Acad Dermatol Venereol. 2013 Oct;27(10):1278-84. doi: 10.1111/j.1468-3083.2012.04708.x. Epub 2012 Sep 25.
7
Oral glycopyrrolate as second-line treatment for primary pediatric hyperhidrosis.
J Am Acad Dermatol. 2012 Nov;67(5):918-23. doi: 10.1016/j.jaad.2012.02.012. Epub 2012 Mar 7.
8
A randomized placebo-controlled trial of oxybutynin for the initial treatment of palmar and axillary hyperhidrosis.
J Vasc Surg. 2012 Jun;55(6):1696-700. doi: 10.1016/j.jvs.2011.12.039. Epub 2012 Feb 16.
9
Systemic therapy for primary hyperhidrosis: a retrospective study of 59 patients treated with glycopyrrolate or clonidine.
J Am Acad Dermatol. 2012 Mar;66(3):387-92. doi: 10.1016/j.jaad.2011.01.023. Epub 2011 Aug 4.
10
The Society of Thoracic Surgeons expert consensus for the surgical treatment of hyperhidrosis.
Ann Thorac Surg. 2011 May;91(5):1642-8. doi: 10.1016/j.athoracsur.2011.01.105.
Zotero 插件