对茄子（茄属龙葵）两种新过敏原蛋白的IgE反应

IgE response to two new allergen proteins of Solanum melongena L. (eggplant).

作者信息

Hoseini-Alfatemi Seyedeh Mahsan, Bayry Jagadeesh, Sharifi-Rad Javad

机构信息

Pediatric Infections Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran 15468-15514, Iran.

Institut National de la Santé et de la Recherche Médicale, Unité 1138, Centre de Recherche des Cordeliers, Paris F-75006, France; Sorbonne Universités, UPMC Univ Paris 06, UMR S 1138, Paris, F-75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris, F-75006, France.

出版信息

Immunol Lett. 2015 Dec;168(2):268-70. doi: 10.1016/j.imlet.2015.10.002. Epub 2015 Oct 8.

DOI:10.1016/j.imlet.2015.10.002

PMID:26455782

Abstract

A number of allergens from eggplant (Solanum melongena L.) have been previously identified. In this study, we could detect IgE reactivity of two allergic subjects' sera towards two protein bands of molecular mass of about 35 and 15 kDa. As IgE were reactive to both raw and cooked eggplant extracts, a heat-stable nature of these novel allergens is apparent.

摘要

此前已鉴定出多种来自茄子（茄属龙葵）的过敏原。在本研究中，我们能够检测到两名过敏受试者血清对两条分子量约为35 kDa和15 kDa的蛋白条带的IgE反应性。由于IgE对生茄子提取物和熟茄子提取物均有反应，这些新型过敏原具有热稳定性是显而易见的。