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使用改良的血压与身高比改善儿童高血压筛查

Improving Hypertension Screening in Childhood Using Modified Blood Pressure to Height Ratio.

作者信息

Dong Bin, Wang Zhiqiang, Wang Hai-Jun, Ma Jun

机构信息

Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, China.

Centre for Chronic Disease, School of Medicine, The University of Queensland, Brisbane, Qld, Australia.

出版信息

J Clin Hypertens (Greenwich). 2016 Jun;18(6):557-64. doi: 10.1111/jch.12712. Epub 2015 Oct 12.

Abstract

Blood pressure to height ratio (BPHR) has been suggested as a simple method for screening children with hypertension, but its discriminatory ability in young children is not as good as that in older children. Using data of 89,664 Chinese children aged 7 to 11 years, the authors assessed whether modified BPHR (BP:eHT13) was better than BPHR in identifying young children with hypertension. BP:eHT13 was estimated as BP/(height+7×(13-age in years)). Using Youden's index, the thresholds of systolic/diastolic BP:eHT13 for identifying prehypertension and hypertension were 0.67/0.44 and 0.69/0.45, respectively. These proposed thresholds revealed high sensitivity, specificity, negative predictive value, and area under the curve (AUC), ranging from 0.874 to 0.999. In addition, BP:eHT13 showed better AUCs and fewer cutoff points than, if not similar to, two existing BPHR references. BP:eHT13 generally performed better than BPHR in discriminating BP abnormalities in young children and may improve early hypertension recognition and control.

摘要

血压与身高比(BPHR)已被提议作为筛查儿童高血压的一种简单方法,但其在幼儿中的鉴别能力不如大龄儿童。作者利用89664名7至11岁中国儿童的数据,评估改良后的BPHR(BP:eHT13)在识别幼儿高血压方面是否优于BPHR。BP:eHT13的计算方法为血压/(身高+7×(13-年龄))。利用约登指数,识别高血压前期和高血压的收缩压/舒张压BP:eHT13阈值分别为0.67/0.44和0.69/0.45。这些提议的阈值显示出高敏感性、特异性、阴性预测值和曲线下面积(AUC),范围在0.874至0.999之间。此外,BP:eHT13的AUC更好,切点数量比现有的两个BPHR参考指标(即便不相似)更少。在鉴别幼儿血压异常方面,BP:eHT13总体上比BPHR表现更好,可能会改善高血压的早期识别和控制。

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