Goldstein Hannah E, Kennedy Benjamin C, Santos Junia, Anderson Richard C E, Feldstein Neil A
Department of Neurosurgery, Morgan Stanley Children's Hospital of New York, Columbia University, New York, NY, USA.
The Neurological Institute, Columbia University Medical Center, 710 West 168th Street, 4th floor, New York, NY, 10032, USA.
Childs Nerv Syst. 2016 Apr;32(4):697-701. doi: 10.1007/s00381-015-2925-x. Epub 2015 Oct 12.
Endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) as a primary treatment for hydrocephalus is gaining popularity in North America, particularly among the infant population. Unfortunately, despite considerable experience with ETV/CPC at several centers, treatment failures still exist. Early reports have suggested that greater than 90 % cauterization of the choroid plexus is associated with improved clinical outcomes. However, individual patient anatomy and smaller overall ventricular size can limit the amount of choroid plexus cauterization that is technically possible through a single frontal burr hole. Furthermore, the degree of cauterization achieved by surgeons using this technique is difficult to quantify objectively. In this report, we describe the case of an infant who failed initial ETV/CPC but then had successful resolution of hydrocephalus after additional choroid plexus cauterization performed through bilateral occipital burr holes. The child remains shunt-free over a year after treatment, suggesting that this three-pronged CPC approach (the "bowling ball" technique) may be successful in some young children with persistent hydrocephalus after ETV/CPC from a single frontal burr hole.
内镜下第三脑室造瘘术联合脉络丛烧灼术(ETV/CPC)作为脑积水的主要治疗方法在北美越来越受欢迎,尤其是在婴儿群体中。不幸的是,尽管多个中心在ETV/CPC方面有相当丰富的经验,但治疗失败的情况仍然存在。早期报告表明,脉络丛烧灼超过90%与临床预后改善相关。然而,个体患者的解剖结构和整体脑室较小会限制通过单个额部钻孔在技术上可行的脉络丛烧灼量。此外,外科医生使用该技术实现的烧灼程度难以客观量化。在本报告中,我们描述了一名婴儿的病例,该婴儿最初的ETV/CPC治疗失败,但在通过双侧枕部钻孔进行额外的脉络丛烧灼后,脑积水成功得到解决。该患儿在治疗后一年多未使用分流器,这表明这种三管齐下的脉络丛烧灼方法(“保龄球”技术)可能对一些在通过单个额部钻孔进行ETV/CPC后仍持续存在脑积水的幼儿有效。