Achong M R, Bayne J R, Gerson L W, Golshani S
Can Med Assoc J. 1978 Jun 24;118(12):1503-8.
The prescribing of psychoactive drugs for 1431 chronically ill elderly patients being assessed for long-term institutional or community care was surveyed. Psychoactive drugs had been prescribed for about one quarter of the patients; benzodiazepines were the most frequently prescribed group. Judging from the extensive prescribing of flurazepam and chloral hydrate, commonly used hypnotics, the main reason psychoactive drugs were prescribed was to provide night-time sedation. Antidepressants and drugs promoted as useful in improving cognitive function were infrequently prescribed. Commendable prescribing practices included the infrequent use of "cerebral vasodilators" and barbiturates. Questionable prescribing practices included the infrequent use of tricyclic antidepressants in severely depressed patients and the use of tranquilizers in patients described by their attending physician as markedly or extremely withdrawn.
对1431名正在接受长期机构或社区护理评估的慢性病老年患者使用精神活性药物的情况进行了调查。约四分之一的患者曾被开具精神活性药物;苯二氮䓬类药物是最常被开具的类别。从常用催眠药氟西泮和水合氯醛的广泛处方情况来看,开具精神活性药物的主要原因是提供夜间镇静。抗抑郁药以及被宣传对改善认知功能有用的药物很少被开具。值得称赞的处方做法包括很少使用“脑血管扩张剂”和巴比妥类药物。有问题的处方做法包括在重度抑郁症患者中很少使用三环类抗抑郁药,以及在主治医生描述为明显或极度孤僻的患者中使用镇静剂。