Gališinová Jana, Čižmárik Jozef, Salanci Eva, Gálusová Andrea, Stopková Lenka, Andriamainty Fils
Ceska Slov Farm. 2015 Sep;64(4):144-8.
Micellization of selected quaternary ammonium compounds derived from heptacaine have been studied by absorption spectroscopy in the UV/VIS spectral region with the use of a pyrene probe. The compounds studied in the aqueous solution have been marked as H22, H26, H27, H29, H34, H + Al and H + B and the derivative marked as H34 was studied in a 3 mol/l ethanol solution at the temperature of 25 °C. In the homologous series of the studied bromides H22, H26, H27 and H29, cmc was observed to be dependent on the number of carbon atoms nc in the hydrophobic chain: ln (cmc) = -3.131-0.421nC. The Free Gibbs energy necessary for the transfer of a methyl group of the alkyl chain from the water phase to the inner part of the micelle at the temperature of 25 °C is (-0.421 ± 0.034)RT.
利用芘探针通过紫外/可见光谱区域的吸收光谱法研究了源自庚卡因的选定季铵化合物的胶束化作用。在水溶液中研究的化合物标记为H22、H26、H27、H29、H34、H + Al和H + B，且在25℃温度下于3mol/l乙醇溶液中研究了标记为H34的衍生物。在所研究的溴化物H22、H26、H27和H29的同系物系列中，观察到临界胶束浓度（cmc）取决于疏水链中碳原子的数量nc：ln(cmc) = -3.131 - 0.421nC。在25℃温度下，将烷基链的甲基从水相转移至胶束内部所需的自由吉布斯能为(-0.421 ± 0.034)RT。
