Härtig F, Purrucker J, Hametner C, Poli S
Abteilung Neurologie mit Schwerpunkt neurovaskuläre Erkrankungen, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72070, Tübingen, Deutschland.
Neurologische Klinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland.
Med Klin Intensivmed Notfmed. 2016 Nov;111(8):703-707. doi: 10.1007/s00063-015-0092-1. Epub 2015 Oct 12.
During the last two decades major efforts in clinical research have led to the establishment of intravenous thrombolysis as the first line acute therapy for ischemic stroke. More recently, data from successful phase III trials have provided proof of the efficiency of mechanical recanalization in acute stroke. The fact that the efficiency of the available therapies can be increased through faster delivery is well documented; however, many institutions dealing with the emergency care of stroke patients lack organizational or infrastructural arrangements to optimize time efficiency in the diagnostic and therapeutic workup.
Many of these arrangements have been well evaluated, can be implemented at reasonable costs and have been proven to increase the beneficial effects of thrombolytic therapy.
在过去二十年中,临床研究的主要努力已使静脉溶栓成为缺血性中风的一线急性治疗方法。最近,来自成功的III期试验的数据证明了急性中风机械再通的有效性。现有治疗方法的效率可通过更快的给药速度提高,这一点已有充分记录;然而,许多处理中风患者急诊护理的机构缺乏优化诊断和治疗工作流程时间效率的组织或基础设施安排。
其中许多安排已得到充分评估,可在合理成本下实施,并已被证明可增强溶栓治疗的有益效果。