Wang Ai-Xiang, Feng Shi-Lou, Chang Ji-Wu
Division of Uropathology, Tianjin Institute of Urologic Surgery, The Second Hospital of Tianjin Medical University Tianjin, China.
Int J Clin Exp Pathol. 2015 Aug 1;8(8):9703-5. eCollection 2015.
Leiomyoma of the bilateral testicular tunica albuginea is extremely rare. To our knowledge, there are only 3 definitely reported cases. This is the first report of bilateral testicular tunica albuginea leiomyomas as a potential cause of male infertility. Herein, we report a case of a 47-year-old man who presented with painless bilateral testicular masses for more than 30 years, besides he also suffered from unexplained infertility. The complete resection of the tumors was performed. The final pathological diagnosis was leiomyomas of the bilateral tunica albuginea. Postoperatively, the patient underwent testicular biopsy. Histopathology confirmed moderate atrophy of bilateral testes, and the number of spermatogenic cells in the seminiferous tubules were significantly decreased. In this case, bilateral testicular dysplasia is the root reason for the patient's infertility. Thus, despite the benign nature of bilateral testicular tunica albuginea leiomyomas, they may cause bilateral testicular hypoplasia and infertility in men. In the case of men with fertility requirements, early local mass excision is often necessary.
双侧睾丸白膜平滑肌瘤极为罕见。据我们所知，仅有3例明确报道的病例。本文首次报道双侧睾丸白膜平滑肌瘤可能是男性不育的原因。在此，我们报告一例47岁男性，其双侧睾丸无痛性肿块已存在30多年，此外还患有不明原因的不育症。对肿瘤进行了完整切除。最终病理诊断为双侧白膜平滑肌瘤。术后，患者接受了睾丸活检。组织病理学证实双侧睾丸中度萎缩，生精小管中生精细胞数量显著减少。在该病例中，双侧睾丸发育异常是患者不育的根本原因。因此，尽管双侧睾丸白膜平滑肌瘤为良性，但它们可能导致男性双侧睾丸发育不全和不育。对于有生育需求的男性患者，早期进行局部肿块切除往往很有必要。
