Avni E F, Van Sinoy M L, Hall M, Stallenberg B, Matos C
Department of Radiology, Erasme Hospital (ULB), Brussels, Belgium.
Pediatr Radiol. 1989;19(2):108-10. doi: 10.1007/BF02387897.
A group of 10 pediatric patients had renal hyperechogenicity and reduced renal mass. The authors wish to suggest a relationship between renal hyperechogenicity and glomerular hyperfiltration according to Brenner's theory on the progressive nature of kidney disease. Reduced renal mass was related to multicystic dysplastic kidney (3 cases) nephrectomy (3 cases) and to reflux nephropathy (4 cases). The hyperechogenicity was diffuse in 6 cases with the preservation of cortico-medullary differentiation and was localized in all four cases of reflux nephropathy producing a "pseudotumoral" appearance. Hyperfiltration was confirmed by isotope studies in all 3 cases where it was performed. This condition together with secondary glomerulosclerosis could explain hyperechogenicity. The predictive value of such patterns are still unclear; yet such findings should lead to appropriate radiolocal, functional, clinical and dietary measures.
一组10名儿科患者出现肾回声增强和肾实质减少。作者希望根据布伦纳关于肾脏疾病进展性质的理论，提出肾回声增强与肾小球高滤过之间的关系。肾实质减少与多囊性发育不良肾（3例）、肾切除术（3例）和反流性肾病（4例）有关。6例肾回声增强呈弥漫性，皮髓质分界保留，4例反流性肾病均呈局限性，产生“假肿瘤”外观。在所有进行同位素研究的3例病例中均证实存在高滤过。这种情况与继发性肾小球硬化一起可以解释肾回声增强。这些模式的预测价值仍不清楚；然而，这些发现应导致采取适当的放射性定位、功能、临床和饮食措施。
