Samoukina A M, Mikhailova E S, Chervinets V M, Alekseeva Yu A
Klin Lab Diagn. 2015 Jun;60(6):57-60.
The study was carried out to analyze qualitative and quantitative parameters of oral fluid and feces in 74 healthy individuals of different age groups. In most of the cases, alterations of micro-ecology are established characterizing by decreasing of amount of indigenous micro-flora and increasing of number of opportunistic pathogenic microorganisms of genera of Staphylococcus, Bacillus, Candida. The degree of evidence of these alterations reliably increases with age. It is established that microbiota, initial and terminal biotopes of digestive tract are closely interrelated and have number of common characteristics depending on age, hormonal and immune status and reflect conditions of micro-biocenosis of digestive tract in general. The character and degree of evidence of alterations of micro-biocenosis can be an effective diagnostic criterion for complex evaluation of human health conditions with following formation of risk groups in need of particular volume of correction activities.
本研究旨在分析74名不同年龄组健康个体口腔液和粪便的定性和定量参数。在大多数情况下,微生态改变表现为固有微生物群落数量减少以及葡萄球菌属、芽孢杆菌属、念珠菌属等机会性致病微生物数量增加。这些改变的证据程度随年龄可靠增加。已确定消化道的微生物群、初始和终末生物群落密切相关,并且根据年龄、激素和免疫状态具有许多共同特征,总体上反映了消化道微生物群落的状况。微生物群落改变的特征和证据程度可作为有效诊断标准,用于综合评估人类健康状况,进而形成需要特定量矫正活动的风险群体。