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脊髓前角缺血

[Ischemia of the anterior horn of the spinal cord].

作者信息

Mathe J F, Fève J R, Labat J J, De Kersaint Gilly A, Potagas C, Dubois C

机构信息

Service de Rééducation Fonctionnelle polyvalente Hôpital Saint Jacques, Nantes.

出版信息

Rev Neurol (Paris). 1989;145(1):60-4.

PMID:2646683
Abstract

Ischemia of the motoneurons in the anterior horn is a well known pathological entity. Their clinical signs and symptoms are similar to those of amyotrophic lateral sclerosis. Evidence by selective angiography of angiomas of the spinal cord or compression or deviation of Adamkiewicz artery may be suggestive of an initial vascular lesion. Various data (knowledge of development or lesions during experimental ischemia, selective electrophysiologic analysis of anterior horn neurons, evidence of precise circumstances of spinal vascular disorder or spinal arteriography) suggest that anterior horn ischemia is a multiple aspect phenomenon. Our 4 cases illustrate this hypothesis and demonstrate under confirmed vascular circumstances the different clinical aspects of anterior horn ischemic lesions. In addition to typical amyotrophic paralysis unusual or misleading symptoms may occur such as claudication, paroxysmal contractures or progressive spastic paraparesis. Investigations required and possible treatment of the lesions are simplified by awareness of these various clinical aspects.

摘要

前角运动神经元缺血是一种众所周知的病理实体。其临床体征和症状与肌萎缩侧索硬化症相似。脊髓血管瘤的选择性血管造影证据或Adamkiewicz动脉受压或移位可能提示最初的血管病变。各种数据(实验性缺血期间的发育或病变知识、前角神经元的选择性电生理分析、脊髓血管疾病的确切情况证据或脊髓血管造影)表明前角缺血是一种多方面的现象。我们的4例病例说明了这一假设,并在已证实的血管情况下展示了前角缺血性病变的不同临床方面。除了典型的肌萎缩性麻痹外,还可能出现不寻常或误导性的症状,如间歇性跛行、阵发性挛缩或进行性痉挛性截瘫。认识到这些不同的临床方面有助于简化对病变所需的检查和可能的治疗。

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