Barrière P, Roch M, L'Hermite A, Sagot P, Lopes P, Charbonnel B
Département de Gynécologie-Obstétrique et Biologie de la Reproduction, CHR, Nantes.
Rev Fr Gynecol Obstet. 1989 Feb;84(2):101-5.
Analysis of several sperm counts makes possible the positive diagnosis of oligo-astheno-teratospermia. Attempts to determine their etiology and consequently their treatment, remain negative, in most cases. The physician involved must then try to answer the couple's concern about the prognosis. The prognosis depends on the alterations seen on the sperm count parameters; but there is no threshold figure under which no pregnancy is observed (except for zero), concerning the count, the gradual mobility or the morphology of the spermatozoids. Motility studies, survival tests in cervical secretions, in the female genital apparatus and in culture media or fertilization in vitro tests, improve the prognosis. However, an answer can only be provided if the fertility takes into account the age of the female partner and a study of her fertility as well as the duration of the infertility. Management will consist of a choice between discontinuation of the treatment, test of fertilization in vitro and temporizing, including trials of male treatment and treatment of possibly associated female factors.
对多次精子计数进行分析有助于对少弱畸精子症做出肯定诊断。然而,在大多数情况下,试图确定其病因并进而进行治疗的尝试均无果。相关医生必须设法回应这对夫妇对预后的担忧。预后取决于精子计数参数所显示的异常情况;但就精子数量、渐进性活力或精子形态而言,不存在一个低于此值就不会观察到妊娠的临界数值(零除外)。活力研究、在宫颈分泌物、女性生殖器官及培养基中的存活试验或体外受精试验,可改善预后。然而,只有在考虑到女性伴侣的年龄及其生育力研究以及不孕持续时间的情况下,才能给出答案。处理方法包括在停止治疗、体外受精试验和等待观察(包括男性治疗试验及对可能相关的女性因素进行治疗)之间做出选择。