Daniels Lori B, Burns Jane C
Division of Cardiology, Department of Medicine, University of California, San Diego.
Circ J. 2015;79(11):2299-305. doi: 10.1253/circj.CJ-15-0996. Epub 2015 Oct 15.
Acute Kawasaki disease (KD) is diagnosed and treated by pediatricians, but decades later, these individuals are presenting to adult cardiologists with a variety of cardiovascular sequelae, including myocardial ischemia and infarction, congestive heart failure secondary to myocardial fibrosis, and claudication because of vascular insufficiency from thrombosed peripheral arteries. There are no clinical trials to guide management, interventions, and medical therapy in this patient population. This review summarizes the emerging information regarding evaluation of the cardiovascular status of adults decades after childhood KD.
急性川崎病(KD)由儿科医生进行诊断和治疗,但几十年后,这些患者却因各种心血管后遗症而就诊于成人心脏病专家处,这些后遗症包括心肌缺血和梗死、心肌纤维化继发的充血性心力衰竭以及因外周动脉血栓形成导致血管功能不全引起的跛行。目前尚无临床试验来指导这一患者群体的管理、干预和药物治疗。本综述总结了有关儿童期患KD几十年后的成年人心血管状况评估的新信息。