Graß S K, Welkoborsky H-J, Bersch C
Klinikum Nordstadt, Klinik für HNO-Heilkunde, regionale plastische Chirurgie, Kopf- und Halschirurgie, Hannover.
Institut für Pathologie, Klinikum Nordstadt, Hannover.
Laryngorhinootologie. 2016 Jan;95(1):37-42. doi: 10.1055/s-0035-1555914. Epub 2015 Oct 15.
Lateral sinus thrombosis (LST) is a rare but threatening complication of an acute mastoiditis or infected cholesteatoma. Currently only very few papers are available in the literature dealing with the systematic investigation of patients with suspected LST. The purpose of the present study was to evaluate the clinical, intraoperative and therapeutic findings of patients with particular disease.
For this retrospective study the clinical records of 7 patients which were admitted for a suspected LST were evaluated. All patients underwent mastoidectomy with exposition of the lateral sinus and investigating of its blood flow.
A LST was confirmed in 4 patients, 3 patients had a phlebitis. Patients with a LST presented additional symptoms beside otalgia, i. e., dizziness, cephalgia, meningism, deafness of the affected ear, and facial nerve paresis. Postoperative MRI scans revealed a recanalization of the sinus in all cases. Although immediate surgery, 2 patients developed a 2-staged brain abscess in the cerebellum.
Clinical symptoms of the SVT are unspecific. In cases of an acute mastoiditis, neurological signs might be pathognomonic and can direct to a LST. Therapeutic concepts comprise intravenous antibiotics and operative elimination of disease. The exposition of the lateral sinus should be performed in any mastoidectomy for a LST in order to scrutinize its blood flow. In case of a thrombosis additional anticoagulative therapy might be indicated. To exclude a 2-staged brain abscess control MRI scans 7 through 14 days postoperatively are recommended.
外侧窦血栓形成(LST)是急性乳突炎或感染性胆脂瘤罕见但具有威胁性的并发症。目前文献中仅有极少数论文涉及对疑似LST患者的系统研究。本研究的目的是评估特定疾病患者的临床、术中及治疗结果。
对于这项回顾性研究,评估了7例因疑似LST入院患者的临床记录。所有患者均接受了乳突切除术,术中暴露外侧窦并检查其血流情况。
4例患者确诊为LST,3例患者患有静脉炎。LST患者除耳痛外还出现其他症状,即头晕、头痛、颈项强直、患侧耳聋及面神经麻痹。术后MRI扫描显示所有病例窦腔均再通。尽管立即进行了手术,但仍有2例患者在小脑出现了二期脑脓肿。
窦静脉血栓形成(SVT)的临床症状不具有特异性。在急性乳突炎病例中,神经系统体征可能具有诊断意义,并可提示LST。治疗方案包括静脉使用抗生素及手术清除病灶。对于疑似LST的任何乳突切除术,均应暴露外侧窦以检查其血流情况。若存在血栓形成,可能需要加用抗凝治疗。为排除二期脑脓肿,建议术后7至14天进行MRI扫描。