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脑干海绵状血管畸形的手术方法

Surgery Approaches to Brainstem Cavernous Malformations.

作者信息

Wang Zhen, Qian Chunhua, Shi Lufeng, Wang Lin, Zhang Jianmin, Wang Yongjie

机构信息

Department of Neurosurgery, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

出版信息

J Craniofac Surg. 2015 Oct;26(7):e577-80. doi: 10.1097/SCS.0000000000002128.

DOI:10.1097/SCS.0000000000002128
PMID:26468826
Abstract

BACKGROUND AND PURPOSE

To summarize our experience in surgery approach to brainstem cavernous malformation (BSCM).

METHODS

A review of 23 consecutive patients with BSCM receiving surgical resection in our center between July of 2003 and June of 2014 was performed.

RESULTS

Suboccipital approach, retrosigmoid approach, infratentorial-supracerebellar approach, Poppen approach, pterional approach, Kawase approach, and interhemispheric transcallosal-third ventrical approach were applied, of which the last 2 approaches being firstly reported in BSCM surgery. Gross total resection was achieved in 22 patients, whereas subtotal resection in 1. Neurologic function was improved in 15 patients, unchanged in 7 patients, and deteriorated in 1 patient. During a mean follow-up of 3.5 years, no recurrence occurred.

CONCLUSIONS

Proper surgery approach is important to assure total resection, protect normal vital structures, and avoid recurrence.

摘要

背景与目的

总结我们在脑干海绵状畸形(BSCM)手术入路方面的经验。

方法

对2003年7月至2014年6月期间在我们中心连续接受手术切除的23例BSCM患者进行回顾性研究。

结果

采用了枕下入路、乙状窦后入路、幕下小脑上入路、Poppen入路、翼点入路、Kawase入路和经胼胝体-第三脑室入路,其中后两种入路首次在BSCM手术中报道。22例患者实现了全切,1例次全切。15例患者神经功能改善,7例患者神经功能无变化,1例患者神经功能恶化。平均随访3.5年,无复发发生。

结论

合适的手术入路对于确保全切、保护正常重要结构及避免复发至关重要。

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Microsurgery vs. Gamma Knife Radiosurgery for the Treatment of Brainstem Cavernous Malformations: A Systematic Review and Meta-Analysis.显微手术与伽玛刀放射外科治疗脑干海绵状血管畸形的系统评价与Meta分析
Front Neurol. 2021 Jan 26;12:600461. doi: 10.3389/fneur.2021.600461. eCollection 2021.
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Pediatric cerebral cavernous malformations: Genetics, pathogenesis, and management.
小儿脑海绵状血管畸形:遗传学、发病机制及治疗
Surg Neurol Int. 2016 Dec 28;7(Suppl 44):S1127-S1134. doi: 10.4103/2152-7806.196921. eCollection 2016.