Sugiura Yasoo, Hashizume Toshinori, Kawai Osamu, Ohkubo Yasuyuki, Fusegawa Hisae, Araki Norihito, Kaseda Shizuka, Nemoto Etsuo
Dept. of Pulmonary and Thoracic Surgery, National Hospital Organization, Kanagawa Hospital.
Gan To Kagaku Ryoho. 2015 Sep;42(9):1095-7.
Case 1: An 86-year-old man was diagnosed with large cell or squamous cell lung cancer of clinical Stage II A.He was administered nanoparticle albumin-bound paclitaxel(nab-PTX)as fourth-line chemotherapy after monochemotherapy with docetaxel, vinorelbine, and S-1.The patient continues to show complete remission at the 15 courses of nab-PTX.Case 2: A 79-year-old man underwent partial resection of the right lower lung, and the pathological diagnosis was large cell lung cancer of pStage I A.However, recurrence in the right lung and multiple lymph node metastases were identified 3 years after the surgery.He was administered nab-PTX as second-line chemotherapy after vinorelbine monotherapy, and he has shown complete remission for a year.Weekly intravenous nab-PTX may be useful in elderly patients with non-small-cell lung cancer.