Sharath B N, Kumar Amv, Ranjini R, Anand S, Sundaram H, Singh S K, Kumar P
Office of World Health Organization Representative to India, New Delhi and Employee's State Insurance Corporation Medical College and Post Graduate Institute of Medical Science and Research, Bangalore, Karnataka, India.
Indian J Med Microbiol. 2015 Oct-Dec;33(4):572-5. doi: 10.4103/0255-0857.167318.
The Revised National Tuberculosis Control Programme (RNTCP) is implementing the External Quality assurance (EQA) and Random blinded re-checking (RBRC) as one of its important component. This nationwide study was conducted to determine (1) the number and types of RBRC errors and (2) the sensitivity and specificity among rechecked slides.
The study was based on the monthly RBRC reports submitted by ~13,000 designated microscopy centres (DMCs) across the country under routine programmatic settings in 2010. The DMCs reports were compiled at district, state and national level.
A total of 11, 89,564 slides were rechecked from 11,039 DMCs. Of which 99.5% of rechecked slides did not have any errors. The sensitivity and specificity of the rechecked slides had 98% sensitivity and 100% specificity.
RBRC is the crucial component of EQA and the results from the programme are found to be satisfactory. Based on the study findings, the earlier value of 80% sensitivity used for calculation of annual sample size for RBRC has been increased to 90% sensitivity. The annual RBRC sample size for DMCs has been increased by 1.5-2 folds.
修订后的国家结核病控制规划（RNTCP）正在实施外部质量保证（EQA）和随机盲法复查（RBRC），作为其重要组成部分之一。开展这项全国性研究是为了确定：（1）RBRC错误的数量和类型；（2）复查玻片之间的敏感性和特异性。
该研究基于2010年全国约13000个指定显微镜检查中心（DMC）在常规项目设置下每月提交的RBRC报告。DMC的报告在地区、邦和国家层面进行汇总。
共对来自11039个DMC的1189564张玻片进行了复查。其中99.5%的复查玻片没有任何错误。复查玻片的敏感性和特异性分别为98%和100%。
RBRC是EQA的关键组成部分，该项目的结果令人满意。基于研究结果，之前用于计算RBRC年度样本量的80%敏感性值已提高到90%敏感性。DMC的年度RBRC样本量增加了1.5至2倍。
