Capoor M R, Gupta D K, Verma P K, Sachdeva H C
Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India.
Indian J Med Microbiol. 2015 Oct-Dec;33(4):576-9. doi: 10.4103/0255-0857.167320.
Systemic fungal infection related to fluconazole-resistant yeasts are emerging in immunocompromised patients. In this case-series, we report eight cases of fungemia caused by Trichosporon spp. (2), Stephanoascus ceferrii (1), Kodamaea ohmeri (1), Pichia kutrawersi (2), Candida rugosa (1) and Candida lusitianae (1) in immunocompromised patients. All the yeasts except (Trichosporon asahii) were sequenced. As these rare species are inherently resistant to antifungal agents and they may lead to the development of nosocomial outbreaks, therefore, accurate identification followed by antifungal susceptibility testing is crucial for proper treatment and management.
免疫功能低下的患者中与氟康唑耐药酵母菌相关的系统性真菌感染正在出现。在本病例系列中，我们报告了8例免疫功能低下患者由毛孢子菌属（2例）、塞弗瑞氏嗜丝酵母（1例）、奥默柯达酵母（1例）、库特拉维尔毕赤酵母（2例）、皱落假丝酵母（1例）和葡萄牙假丝酵母（1例）引起的真菌血症。除阿萨希毛孢子菌外，所有酵母菌均进行了测序。由于这些罕见菌种本身对抗真菌药物耐药，且可能导致医院感染暴发，因此，准确鉴定并随后进行抗真菌药敏试验对于正确的治疗和管理至关重要。
