• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Amphotericin B induction of sensitivity to adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) plus cyclophosphamide in human neoplasia.

作者信息

Presant C A, Klahr C, Santala R

出版信息

Ann Intern Med. 1977 Jan;86(1):47-51. doi: 10.7326/0003-4819-86-1-47.

DOI:10.7326/0003-4819-86-1-47
PMID:264783
Abstract

Seven patients with metastatic tumors resistant to therapy with adriamycin, BCNU, plus cyclophosphamide received the same chemotherapy combined with amphotericin B. One complete response (acute myelomonocytic leukemia), two partial responses (carcinoma of the breast and multiple myeloma), and one case with objective improvement (carcinoma of the breast) were observed in seven evaluable trials. Myelosuppression was not consistently changed by addition of amphotericin B. Fever and chills were common after amphotericin B. Bronchospasm and hypotension occurred twice. Amphotericin B reverses resistance to adriamycin-containing chemotherapy regimens in some patients.

摘要

相似文献

1
Amphotericin B induction of sensitivity to adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) plus cyclophosphamide in human neoplasia.
Ann Intern Med. 1977 Jan;86(1):47-51. doi: 10.7326/0003-4819-86-1-47.
2
Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU-NSC 409462), and cyclophosphamide in refractory adenocarcinoma of the breast and other tumors.
Cancer. 1976 Feb;37(2):620-8. doi: 10.1002/1097-0142(197602)37:2<620::aid-cncr2820370203>3.0.co;2-d.
3
Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962) and cyclophosphamide therapy of drug-resistant metastatic breast carcinoma.
Cancer. 1977 Sep;40(3):987-93. doi: 10.1002/1097-0142(197709)40:3<987::aid-cncr2820400304>3.0.co;2-0.
4
Amphotericin B plus 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU-NSC no. 409962) in advanced cancer. Phase I and preliminary phase II results.
Cancer. 1976 Nov;38(5):1917-21. doi: 10.1002/1097-0142(197611)38:5<1917::aid-cncr2820380508>3.0.co;2-s.
5
Adriamycin, 1,3-bis (2-chloroethyl) 1 nitrosourea (BCNU, NSC No. 409962), cyclophosphamide plus prednisone (ABC-P) in melphalanresistant multiple myeloma.
Cancer. 1978 Sep;42(3):1222-7. doi: 10.1002/1097-0142(197809)42:3<1222::aid-cncr2820420329>3.0.co;2-k.
6
Phase II study of 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC No. 409962) with amphotericin B in bronchogenic carcinoma.
Cancer. 1980 Jan 1;45(1):6-10. doi: 10.1002/1097-0142(19800101)45:1<6::aid-cncr2820450103>3.0.co;2-y.
7
Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma.两性霉素B与联合化疗治疗难治性转移性乳腺癌和肉瘤
Cancer Treat Rep. 1978 Oct;62(10):1565-7.
8
Adriamycin, BCNU, and cyclophosphamide in drug-resistant adenocarcinoma of the ovary.
Med Pediatr Oncol. 1983;11(3):151-3. doi: 10.1002/mpo.2950110302.
9
Response of transplanted AKR leukemia to combination therapy with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea: dose and schedule dependency.
J Natl Cancer Inst. 1977 Apr;58(4):949-53. doi: 10.1093/jnci/58.4.949.
10
Growth and rejection of leukemia cells in individual mice after combined treatment with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea.
J Natl Cancer Inst. 1978 Aug;61(2):399-402.

引用本文的文献

1
Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.常规两性霉素 B 可诱导白血病细胞发生免疫原性细胞死亡，介导吞噬细胞的免疫刺激作用，并与 PD-L1 阻断协同作用。
Oncoimmunology. 2022 Apr 25;11(1):2068109. doi: 10.1080/2162402X.2022.2068109. eCollection 2022.
2
Potentiation of cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) by amphotericin B in BALB/c nude mice bearing human ovarian carcinoma cells.两性霉素B对携带人卵巢癌细胞的BALB/c裸鼠体内顺二氨（1,1-环丁烷二羧酸根）铂（II）的增效作用
Jpn J Cancer Res. 1994 Nov;85(11):1159-64. doi: 10.1111/j.1349-7006.1994.tb02922.x.
3
Amphotericin B plus combination chemotherapy for extensive non-small cell bronchogenic carcinoma.
Cancer Chemother Pharmacol. 1980;5(2):89-92. doi: 10.1007/BF00435410.
4
Effects of amphotericin B on hepatitis B virus.两性霉素B对乙型肝炎病毒的作用。
Antimicrob Agents Chemother. 1981 Dec;20(6):826-33. doi: 10.1128/AAC.20.6.826.
5
Candida infection in surgical patients.外科患者的念珠菌感染。
World J Surg. 1980 Jul;4(4):381-94. doi: 10.1007/BF02393155.
6
Modulation of macrophage tumoricidal capability by polyene antibiotics: support for membrane lipid as a regulatory determinant of macrophage function.多烯抗生素对巨噬细胞杀肿瘤能力的调节作用：支持膜脂作为巨噬细胞功能的调节决定因素。
Proc Natl Acad Sci U S A. 1978 Sep;75(9):4349-53. doi: 10.1073/pnas.75.9.4349.
7
Effects of amphotericin B and its methyl ester on the antiviral activity of polyinosinic:polycytidylic acid.两性霉素B及其甲酯对聚肌苷酸:聚胞苷酸抗病毒活性的影响。
Antimicrob Agents Chemother. 1979 Aug;16(2):203-9. doi: 10.1128/AAC.16.2.203.
8
Antineoplastic drugs: clinical pharmacology and therapeutic use.抗肿瘤药物：临床药理学与治疗应用
Drugs. 1978 Jul;16(1):46-87. doi: 10.2165/00003495-197816010-00003.