一种基于用Fe(II)交换的X型沸石纳米颗粒修饰碳糊电极的新型半胱氨酸传感器。
A novel cysteine sensor based on modification of carbon paste electrode by Fe(II)-exchanged zeolite X nanoparticles.
作者信息
Hashemi Habibeh-Sadat, Nezamzadeh-Ejhieh Alireza, Karimi-Shamsabadi Maryam
机构信息
Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Young Researchers and Elite Club, Shahreza Branch, Islamic Azad university, P.O. Box 311-86145, Shahreza, Isfahan, Iran.
Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Razi Chemistry Research Center (RCRC), Shahreza Branch, Islamic Azad University, Isfahan, Iran.
出版信息
Mater Sci Eng C Mater Biol Appl. 2016 Jan 1;58:286-93. doi: 10.1016/j.msec.2015.08.051. Epub 2015 Aug 31.
An electrochemical sensor based on carbon paste electrode (CPE) modified with iron(II) doped into a synthesized nano-particles of zeolite X (Fe(II)-NX/ZCME) was constructed, which is highly sensitive for detection of cysteine (Cys). The modified electrode showed an excellent electro-activity for oxidation of Cys in phosphate buffer at pH7.4. It has been found that anodic peak potential of Cys oxidation, compared with the unmodified CPE (UCPE), was shifted towards negative values at the surface of the modified electrode under the optimum condition. The peak current increased linearly with the Cys concentration in the wide range of 5.0 × 10(-9)-3.0 × 10(-3) mol L(-1). The very low detection limit was obtained to be 1.5 × 10(-10) mol L(-1). Finally, the modified electrode was used as a selective, simple and precise new electrochemical sensor for the determination of Cys in the real samples, such as pharmaceutical and biological fluids.
构建了一种基于用掺杂亚铁离子的合成X型沸石纳米颗粒（Fe(II)-NX/ZCME）修饰的碳糊电极（CPE）的电化学传感器，该传感器对检测半胱氨酸（Cys）具有高度敏感性。修饰电极在pH7.4的磷酸盐缓冲液中对Cys的氧化表现出优异的电活性。研究发现，在最佳条件下，与未修饰的CPE（UCPE）相比，修饰电极表面Cys氧化的阳极峰电位向负值方向移动。在5.0×10(-9)-3.0×10(-3) mol L(-1)的宽范围内，峰电流与Cys浓度呈线性增加。获得了非常低的检测限，为1.5×10(-10) mol L(-1)。最后，该修饰电极被用作一种选择性好、简单且精确的新型电化学传感器，用于测定实际样品（如药物和生物流体）中的Cys。
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