单倍型相合造血干细胞移植治疗获得性重型再生障碍性贫血免疫抑制治疗无效者 - Suppr

Haploidentical hematopoietic stem cell transplantation for nonresponders to immunosuppressive therapy against acquired severe aplastic anemia.

作者信息

Liu L, Wang X, Jin S, Hao L, Zhang Y, Zhang X, Wu D

机构信息

Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Collaborative Innovation Center of Hematology, Jiangsu Institute of Hematology, Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Department of Hematology, The Second People's Hospital of Huai'an, Huai'an, China.

出版信息

Bone Marrow Transplant. 2016 Mar;51(3):424-7. doi: 10.1038/bmt.2015.249. Epub 2015 Oct 19.

DOI:10.1038/bmt.2015.249

PMID:26479978

Abstract

摘要

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Haploidentical hematopoietic stem cell transplantation for nonresponders to immunosuppressive therapy against acquired severe aplastic anemia.

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Conditioning including antithymocyte globulin followed by unmanipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes with HLA-identical sibling transplantation.

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Haploidentical hematopoietic stem cell transplantation for nonresponders to immunosuppressive therapy against acquired severe aplastic anemia.

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