Kubo A, Kuma E, Nakagawa H, Kagaya T, Yazawa C, Toyosawa T, Mizuguchi K
Dept. of Int. Med., Tokyo Metropolitan Fuchu Hospital.
Gan No Rinsho. 1989 Feb;35(3):427-35.
Reported is a case of a 73-year-old male with a history of ulcerative colitis that had started at the age of 57. In 1985, on receiving a barium enema, a polypoid lesion was found in his rectum. In 1986, the results of a colonoscopy showed that the polypoid lesion had reached an IIa-aggregated elevation, and biopsies of this lesion were diagnosed as an adenoma or a hyperplastic polyp. A year later, in 1987, another biopsy specimen was taken and was histologically diagnosed as being an adenomatous cancer. Thus, a pull-through operation and a cholecystectomy were performed. The lesion was 4.5 x 3.0 cm in diameter, and the histological findings showed it to be a well-differentiated adenocarcinoma with a submucosal invasion. Accordingly, physicians should be advised that patients with a longstanding ulcerative colitis ought to undergo periodic examination that includes a colonoscopy and a biopsy of any suspicious growth.
报告了一例73岁男性患者，其溃疡性结肠炎病史始于57岁。1985年，在接受钡灌肠检查时，发现其直肠有一个息肉样病变。1986年，结肠镜检查结果显示该息肉样病变已发展为IIa型聚集性隆起，对该病变进行活检诊断为腺瘤或增生性息肉。一年后的1987年，又取了一份活检标本，组织学诊断为腺瘤性癌。于是，进行了经腹会阴联合切除术和胆囊切除术。病变直径为4.5×3.0厘米，组织学检查结果显示为高分化腺癌，侵犯黏膜下层。因此，应建议医生，患有长期溃疡性结肠炎的患者应定期进行检查，包括结肠镜检查和对任何可疑肿物进行活检。
