Irazuzta Jose E, Brown Martha E, Akhtar Javed
Department of Pediatrics, University of Florida, Division of Pediatric Critical Care, Jacksonville, Florida.
Department of Pediatrics, University of Florida, Division of Pediatric Critical Care, Jacksonville, Florida.
Pediatr Neurol. 2016 Jan;54:35-8. doi: 10.1016/j.pediatrneurol.2015.08.009. Epub 2015 Aug 28.
We determined whether the bedside assessment of the optic nerve sheath diameter could identify elevated intracranial pressure in individuals with suspected idiopathic intracranial hypertension.
This was a single-center, prospective, rater-blinded study performed in a freestanding pediatric teaching hospital. Patients aged 12 to 18 years scheduled for an elective lumbar puncture with the suspicion of idiopathic intracranial hypertension were eligible to participate. Optic nerve sheath diameter was measured via ultrasonography before performing a sedated lumbar puncture for measuring cerebrospinal fluid opening pressure. Abnormal measurements were predefined as optic nerve sheath diameter ≥4.5 mm and a cerebrospinal fluid opening pressure greater than 20 cmH2O.
Thirteen patients participated in the study, 10 of whom had elevated intracranial pressure. Optic nerve sheath diameter was able to predict or rule out elevated intracranial pressure in all patients.
Noninvasive assessment of the optic nerve sheath diameter could help to identify patients with elevated intracranial pressure when idiopathic intracranial hypertension is suspected.
我们确定视神经鞘直径的床旁评估能否识别疑似特发性颅内高压患者的颅内压升高情况。
这是一项在一家独立的儿科教学医院进行的单中心、前瞻性、评估者盲法研究。计划接受择期腰椎穿刺且怀疑患有特发性颅内高压的12至18岁患者有资格参与。在进行镇静腰椎穿刺以测量脑脊液初压之前，通过超声测量视神经鞘直径。异常测量结果预先定义为视神经鞘直径≥4.5毫米且脑脊液初压大于20厘米水柱。
13名患者参与了该研究，其中10名患者颅内压升高。视神经鞘直径能够在所有患者中预测或排除颅内压升高情况。
对视神经鞘直径进行无创评估有助于在怀疑特发性颅内高压时识别颅内压升高的患者。
